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75892

Sigma-Aldrich

α-Ketoglutaric acid disodium salt dihydrate

≥98.0% (dried material, NT)

Synonym(s):

2-Oxoglutaric acid disodium salt, Sodium α-ketoglutarate dibasic

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About This Item

Linear Formula:
NaOOCCH2CH2COCOONa · 2H2O
CAS Number:
1282616-74-3
Molecular Weight:
226.09
Beilstein/REAXYS Number:
5658566
EC Number:
206-167-8
MDL number:
MFCD00150702
UNSPSC Code:
12352100
PubChem Substance ID:
57652590
NACRES:
NA.22

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Quality Level

200

assay

≥98.0% (dried material, NT)

form

powder

impurities

~16% water

functional group

ketone

SMILES string

O.O.[Na+].[Na+].[O-]C(=O)CCC(=O)C([O-])=O

InChI

1S/C5H6O5.2Na.2H2O/c6-3(5(9)10)1-2-4(7)8;;;;/h1-2H2,(H,7,8)(H,9,10);;;2*1H2/q;2*+1;;/p-2

Inchi Key

HSSWOFWCOAQLHZ-UHFFFAOYSA-L

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This Item
K2010K187590790
α-Ketoglutaric acid disodium salt dihydrate ≥98.0% (dried material, NT)

Sigma-Aldrich

75892

α-Ketoglutaric acid disodium salt dihydrate

α-Ketoglutaric acid sodium salt BioUltra

Sigma-Aldrich

K2010

α-Ketoglutaric acid sodium salt

α-Ketoglutaric acid sodium salt ≥98% (titration)

Sigma-Aldrich

K1875

α-Ketoglutaric acid sodium salt

L-α-Hydroxyglutaric acid disodium salt ≥98.0% (GC)

Sigma-Aldrich

90790

L-α-Hydroxyglutaric acid disodium salt

assay

≥98.0% (dried material, NT)

assay

≥98% (perchloric acid titration)

assay

≥98% (titration)

assay

≥98.0% (GC)

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

100

form

powder

form

powder

form

powder

form

powder or crystals

impurities

~16% water

impurities

≤0.0005% Phosphorus (P), ≤0.1% Insoluble matter

impurities

-

impurities

≤6.0% water

functional group

ketone

functional group

-

functional group

-

functional group

-

General description

α-Ketoglutaric acid disodium salt dihydrate (2-Oxoglutaric acid disodium salt) is the hydrated disodium salt of 2-oxoglutaric acid.

Application

α-Ketoglutaric acid disodium salt dihydrate (2-Oxoglutaric acid disodium salt) may be used as starting reagent for the synthesis of deuteriated 2-oxo[3,3-2H2]glutarate disodium salt.[1]
α-Ketoglutaric acid disodium salt dihydrate is suitable reagent used in a study to investigate the role of nitric oxide (NO) in mast cell physiology and biochemistry.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN8267
BCCN6048
BCCM9326
BCCL5657
BCCM6264

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Kisakurek MV.
Hominatio: An International Tribute to Albert Eschenmoser, 2557-2557 (2001)
Piotr Dobrowolski et al.
Nutrition (Burbank, Los Angeles County, Calif.), 29(3), 556-561 (2012-12-12)
Proton-pump inhibitors, such as omeprazole, are widely used in the prevention and treatment of gastroesophageal diseases. However, an association between proton-pump inhibitors and the increased risk of bone fractures has been observed, especially in patients treated for extended periods. Conversely
Li-Li Chen et al.
Journal of molecular modeling, 19(4), 1919-1927 (2013-01-23)
Bacillus subtilis natto is widely used in industry to produce natto, a traditional and popular Japanese soybean food. However, during its secondary fermentation, high amounts of ammonia are released to give a negative influence on the flavor of natto. Glutamate
Ming-Ming Jin et al.
Molecular biology reports, 40(4), 2995-3002 (2012-12-25)
Microcystis aeruginosa is the key symptom of water eutrophication and produces persistent microcystins. Our special attention was paid to the isocitrate dehydrogenase (IDH) of M. aeruginosa (MaIDH) because it plays important roles in energy and biosynthesis metabolisms and its catalytic
R V Durán et al.
Oncogene, 32(38), 4549-4556 (2012-10-23)
Hypoxia-inducible factor (HIF) prolyl hydroxylases (PHDs) are α-ketoglutarate (αKG)-dependent dioxygenases that function as cellular oxygen sensors. However, PHD activity also depends on factors other than oxygen, especially αKG, a key metabolic compound closely linked to amino-acid metabolism. We examined the
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