761060

(Tributylphosphoranylidene)acetonitrile

97%

• Synonym(s): (Cyanomethylene)tributylphosphorane
• Empirical Formula (Hill Notation): C₁₄H₂₈NP
• CAS Number: 157141-27-0
• Molecular Weight: 241.35
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 97%
• form: liquid
• refractive index: n20/D 1.500 (lit.)
• density: 0.921 g/mL at 25 °C
• storage temp.: 2-8°C

Description

General description

(Tributylphosphoranylidene)acetonitrile or cyanomethylenetrimethylphosphorane (Bu₃P=CHCN) is a Wittig reagent employed in the transformation of the carbonyl compounds, including aldehydes, esters, and lactones into the corresponding unsaturated nitriles.

Application

(Tributylphosphoranylidene)acetonitrile can be utilized as a reagent in the:

• Stereoselective synthesis of skytanthine and other O- and N-containing heterocycles by Mitsunobu intramolecular cycloalkylation.
• Wittig olefination of esters, lactones, N-Boc lactam, and cyclic imide to corresponding Wittig products.

Packaging

500 mg in glass bottle

1 g in glass bottle

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable