76172

O-(2-Aminoethyl)-O′-(2-azidoethyl)pentaethylene glycol

≥90% (oligomer purity)

• Synonym(s): Azido-PEG-amine (n=6)
• Empirical Formula (Hill Notation): C₁₄H₃₀N₄O₆
• CAS Number: 957486-82-7
• Molecular Weight: 350.41
• MDL number: MFCD03453240
• UNSPSC Code: 12352200
• PubChem Substance ID: 57652623
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: ≥90% (oligomer purity)
• form: liquid
• reaction suitability: reaction type: click chemistry; reagent type: cross-linking reagent
• functional group: amine; azide
• storage temp.: 2-8°C
• SMILES string: NCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
• InChI: 1S/C14H30N4O6/c15-1-3-19-5-7-21-9-11-23-13-14-24-12-10-22-8-6-20-4-2-17-18-16/h1-15H2
• InChI key: VCQSTKKJKNUQBI-UHFFFAOYSA-N

Description

Application

O-(2-Aminoethyl)-O′-(2-azidoethyl)pentaethylene glycol can be used:

• As a reactant for the synthesis of thin films of azide functionalized poly(L-glutamic acid) for drug delivery.[1]
• For the synthesis of curcumin monoazide derivatives for fabricating biologically active curcumin conjugates.[2]
• To modify the surface of TiO₂ nanoparticles to attach DNA strands for photocatalytic reduction of CO₂.[3]
• For the conjugation of poly(ethylene glycol) (PEG) with toll-like receptor 7 (TLR7) to improve its pharmaceutical properties.[4]

O-(2-Aminoethyl)-O′-(2-azidoethyl)pentaethylene glycol has been used in the synthesis of Alexa568-azide, a fluorescent azide that can undergo click staining reaction with 5-ethynyluridine-labeled cellular RNA.[5][6]

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315 - H319 - H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter