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765112

Sigma-Aldrich

Poly(L-lactide)

average Mn 10,000, PDI ≤1.1

Synonym(s):
PLA, PLLA, Polylactide, L-Lactide polymer, PLA, Poly(L-Lactic acid)
Linear Formula:
H(C3H4O2)nOCH3
NACRES:
NA.23

form

solid

Quality Level

optical activity

[α]22/D -150°, c = 0.5% in chloroform

mol wt

average Mn 10,000

degradation timeframe

>3 years

transition temp

Tm 162-167 °C

PDI

≤1.1

storage temp.

2-8°C

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General description

Poly (L-lactide) is a semi-crystalline polymer which exhibits strong optical rotation and good mechanical properties. It is mostly used in the synthesis of degradable polymers which are used in orthopaedic devices, in dental applications, as scaffolds for autografted new skin, wound covers, anastomose systems and stents. They are biodegradable since the polyester backbone degrades by simple hydrolysis to form non-toxic compounds.

Application

Drug Delivery including coating nanoparticles; end-group functionalization; macroinitiator or block precursor.

Packaging

5 g in glass bottle

Features and Benefits

High initial strength, good strength retention and high amount of crystallinity, as much as 70%, which in turn is responsible for the very slow degradation rate.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

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Certificate of Origin

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