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765538

Sigma-Aldrich

Gold nanoparticles

30 nm diameter, carboxylic acid functionalized, PEG 3000 coated, OD 50, dispersion in H2O

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Synonym(s):
Gold nanoparticles COOH functionalized, Au NP COOH, Gold Colloid
NACRES:
NA.23

material

PEG 3000

form

dispersion in H2O
nanoparticles

packaging

poly bottle of 1 mL

OD

50

diameter

30 nm

pH

6.0-8.0 (25 °C)

solubility

water: miscible

density

1.00 g/cm3

λmax

525 nm

functional group

carboxyl

storage temp.

2-8°C

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This Item
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Gold nanoparticles 30 nm diameter, carboxylic acid functionalized, PEG 3000 coated, OD 50, dispersion in H2O

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Gold nanoparticles 10 nm diameter, carboxylic acid functionalized, PEG 3000, OD 50, dispersion in H2O

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Gold nanoparticles

Gold nanoparticles 20 nm diameter, carboxylic acid functionalized, PEG 5000 coated, OD 50, dispersion in H2O

Sigma-Aldrich

765511

Gold nanoparticles

Gold nanoparticles 50 nm diameter, carboxylic acid functionalized, PEG 5000 coated, dispersion in H2O

Sigma-Aldrich

765589

Gold nanoparticles

functional group

carboxyl

functional group

carboxyl

functional group

carboxyl

functional group

carboxyl

material

PEG 3000

material

PEG 3000

material

PEG 5000

material

PEG 5000

packaging

poly bottle of 1 mL

packaging

glass bottle of 1 mL

packaging

poly bottle of 1 mL

packaging

poly bottle of 1 mL

OD

50

OD

50

OD

50

OD

50

diameter

30 nm

diameter

10 nm

diameter

20 nm

diameter

50 nm

General description

Carboxylic acid functionalized GNPs forms conjugates with various protein molecules due to the electrostatic attraction between negatively charged carboxylate groups and positively charged amino groups of protein.

Application

Gold nanoparticles 30 nm diameter, carboxylic acid functionalized, PEG 3000 coated, OD 50, dispersion in H2O can be potentially used in the development of biosensors, cancer-cell imaging, drug delivery, and photothermal therapy.
AuNPs may also be used in the immobilization of antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. It can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization.
The carboxylic acid group binds with various proteins and are used in targeted drug delivery and gene therapy.
Functionalized Particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery.

Features and Benefits

Decreases the cytotoxicity and increases efficiency of GNPs in targeted drug delivery. PEG increases the stability of the nanoparticles and prevents agglomeration.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Nóra Adányi et al.
Food chemistry, 267, 10-14 (2018-06-24)
Mycotoxins, present in a wide range of food and feed commodities, are toxic secondary metabolites produced by a number of different fungi. Certain mycotoxins do not readily degrade at high temperatures, therefore are resistant to food processing, and consequently are
Optical Fiber Sensors for Rapid Screening of COVID-19
Nag P, et al.
Transactions of the Indian National Academy of Engineering, 6, 1-4 (2020)
Size-dependent in vivo toxicity of PEG-coated gold nanoparticles
Zhang X, et al.
International journal of nanomedicine, 6, 2071-2071 (2011)
Nishima Wangoo et al.
Journal of colloid and interface science, 323(2), 247-254 (2008-05-20)
We report a novel strategy for the synthesis of aqueous stable, carboxylated gold nanoparticles (GNPs) by using glutamic acid as the reducing agent. The ratio of chloroaurate ions, AuCl(-)(4) to glutamic acid was optimized in the reaction medium to obtain
Functionalized gold nanoparticles and their biomedical applications
Tiwari, P. M., Vig, K., Dennis, V. A., & Singh, S. R.
Nanomaterials, 1(1), 31-63 (2011)

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