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766305

Sigma-Aldrich

Bis(2-cyanoethyl)-N,N-diisopropylphosphoramidite

95%

Synonym(s):
Bis(2-cyanoethoxy)(diisopropylamino)phosphine, Bis(2-cyanoethoxy)-N,N-diisopropylaminophosphine
Empirical Formula (Hill Notation):
C12H22N3O2P
CAS Number:
Molecular Weight:
271.30
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

95%

form

liquid

refractive index

n20/D 1.465

density

1.039 g/mL at 25 °C

storage temp.

−20°C

SMILES string

CC(C)N(C(C)C)P(OCCC#N)OCCC#N

InChI

1S/C12H22N3O2P/c1-11(2)15(12(3)4)18(16-9-5-7-13)17-10-6-8-14/h11-12H,5-6,9-10H2,1-4H3

InChI key

LDHWBEHZLFDXCU-UHFFFAOYSA-N

General description

Useful phosphorylating reagent used in oligonucleotide synthesis for adding a terminal phosphate group to the 3′ or 5′ hydroxyl.

Application

Bis(2-cyanoethyl)-N,N-diisopropylphosphoramidite may be used as a phosphitylating agent during the multi-step synthesis of (-)-1L-chiro-inositol 2,3,5-trisphosphate starting from L-quebrachitol.

Packaging

1, 5 g in glass bottle

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

165.0 °F

Flash Point(C)

73.9 °C

Certificate of Analysis

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Certificate of Origin

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