The solubility parameters for this product have not been determined. However, this product can be solubilized in ethyl acetate, chloroform, acetone, and THF.
769819
Resomer® RG 753 H, Poly(D,L-lactide-co-glycolide)
acid terminated
Synonym(s):
Resomer® RG 753 H, PLGA
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About This Item
Linear Formula:
HO[C2H4O2]n[C2H2O2]mH
CAS Number:
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.23
Pricing and availability is not currently available.
Quality Level
form
amorphous
feed ratio
lactide:glycolide 75:25
viscosity
0.32-0.44 dL/g
transition temp
Tg 44-55 °C
storage temp.
2-8°C
SMILES string
O2C(C(=O)OC(C2=O)C)C.O1CC(=O)OCC1=O
InChI
1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2
InChI key
LCSKNASZPVZHEG-UHFFFAOYSA-N
Application
Resomer® RG 753 H, Poly(D,L-lactide-co-glycolide) is a biodegradable and biocompatible aliphatic polyester, which can be used in the development of nano and microparticles. It is a pharmaceutical polymer, which finds potential usage in drug delivery and gene delivery. It forms a three-dimensional porous scaffold, which can be used in tissue engineering.
Legal Information
RESOMER is a registered trademark of Evonik Rohm GmbH
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This Item | |||
|---|---|---|---|
| viscosity 0.32-0.44 dL/g | viscosity 0.32-0.44 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer) | viscosity 0.50-0.70 dL/g | viscosity 0.14-0.22 dL/g, 0.5 % in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer) |
| form amorphous | form amorphous | form amorphous | form (Powder or Solid or Chunk(s)) |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| transition temp Tg 44-55 °C | transition temp Tg 46-50 °C | transition temp Tg 48-54 °C | transition temp Tg 42-46 °C |
| feed ratio lactide:glycolide 75:25 | feed ratio lactide:glycolide 65:35 | feed ratio lactide:glycolide 75:25 | feed ratio lactide:glycolide 75:25 |
| Quality Level 100 | Quality Level 200 | Quality Level 100 | Quality Level 200 |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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In vitro degradation of three-dimensional porous poly (D, L-lactide-co-glycolide) scaffolds for tissue engineering
Wu L and Ding J
Biomaterials, 25(27), 5821-5830 (2004)
Nano/micro technologies for delivering macromolecular therapeutics using poly (D, L-lactide-co-glycolide) and its derivatives
Mundargi RC, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 125(3), 193-209 (2008)
Nanoparticles made of fluorescence-labelled poly (L-lactide-co-glycolide): preparation, stability, and biocompatibility
Weiss B, et al.
Journal of Nanoscience and Nanotechnology, 6(9-10), 3048-3056 (2006)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 769819-1G | 04061826139547 |
| 769819-5G | 04061832929699 |
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What is the solubility parameter for polymers in different solvents?
1 answer-
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Was ist das Molekulargewicht vom Polymer?
1 answer-
The molecular weight is reported on the lot-specific Certificate of Analysis. Please navigate to the ‘DOCUMENTATION’ section of the Product Detail Page to access a Certificate:
https://www.sigmaaldrich.com/product/aldrich/769819#product-documentationHelpful?
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What is the solubility parameter for polymers in different solvents?
1 answer-
The solubility parameters for this product have not been determined. However, various sources state this product can be solubilized in ethyl acetate, chloroform, acetone and THF. Please see the link below to learn more about Resomer Biodegradable Polymers: https://www.sigmaaldrich.com/US/en/technical-documents/technical-article/materials-science-and-engineering/drug-delivery/resomer
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