773204

2,2-Bis(aminoethoxy)propane

≥98%

• Synonym(s): 2,2′-[(1-Methylethylidene)bis(oxy)]bis(ethanamine), 2,2-Di(2-aminoethoxy)propane, Diamino ketal
• Empirical Formula (Hill Notation): C₇H₁₈N₂O₂
• CAS Number: 127090-71-5
• Molecular Weight: 162.23
• MDL number: MFCD20694614
• UNSPSC Code: 12162002
• PubChem Substance ID: 329767610
• NACRES: NA.23

Properties

• assay: ≥98%
• form: liquid
• refractive index: n20/D 1.458
• bp: 202-214/760 mmHg
• density: 1.018 g/mL at 25 °C
• SMILES string: CC(C)(OCCN)OCCN
• InChI: 1S/C7H18N2O2/c1-7(2,10-5-3-8)11-6-4-9/h3-6,8-9H2,1-2H3
• InChI key: YDMYVTCIPQGGPB-UHFFFAOYSA-N

Description

General description

2,2-Bis(aminoethoxy)propane is an acid degradable amine monomer that can be used as a ketal containing cross-linker. It is a pH sensitive molecule that is used in the synthesis of polyurea and polyurethane.[1][2]

Application

2,2-Bis(aminoethoxy)propane can be used in the preparation of biocompatible polymeric materials for the development of controlled drug delivery systems.[1][2][3][4]

This homobifunctionalized amino ketal is primarily used in crosslinking cell lysate (linking polypeptides whose lysine side chains are nearest to each other). Primary amines commonly conjugate through acylation or alkylation of isothiocyanates; isocyanates; acyl azides; NHS esters; sulfonyl chlorides; aldehydes; carbonates; aryl halides; imidoesters; carbodiimides; anhydrides; and fluorophenyl esters. This diamine can also crosslink epoxies.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 224.0 °F
• flash_point_c: 106.67 °C