95% (HPLC)

Empirical Formula (Hill Notation):
Molecular Weight:
PubChem Substance ID:

Quality Level


95% (HPLC)

reaction suitability

reaction type: click chemistry

ε (extinction coefficient)



λex 647 nm; λem 663 nm

storage temp.


SMILES string




InChI key


Related Categories


Azide modified cyanine dye that can be used to detect or label alkyne- or cyclooctyne-containing molecules or biomolecules by fluorescence spectroscopy following azide-alkyne cycloaddition.

Solubility: DMSO, DMF, MeOH


5 mg in glass insert
1 mg in amber glass bottle


Exclamation mark

Signal Word


Hazard Statements

Precautionary Statements

Target Organs

Respiratory system


NONH for all modes of transport

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Shanqiao Wei et al.
PloS one, 12(9), e0185010-e0185010 (2017-09-20)
Most B cell cancers overexpress the enzyme activation-induced deaminase at high levels and this enzyme converts cytosines in DNA to uracil. The constitutive expression of this enzyme in these cells greatly increases the uracil content of their genomes. We show...
Markus Muttenthaler et al.
Australian journal of chemistry, 73(4), 327-333 (2020-05-13)
In-solution conjugation is the most commonly used strategy to label peptides and proteins with fluorophores. However, lack of site-specific control and high costs of fluorophores are recognised limitations of this approach. Here, we established facile access to grams of Cy5-COOH...
Valentina M Farzan et al.
Bioconjugate chemistry, 28(10), 2599-2607 (2017-09-19)
We developed a novel technique for the efficient conjugation of oligonucleotides with various alkyl azides such as fluorescent dyes, biotin, cholesterol, N-acetylgalactosamine (GalNAc), etc. using copper-catalysed alkyne-azide cycloaddition on the solid phase and CuI·P(OEt)
Tom van der Wel et al.
Nature communications, 11(1), 3216-3216 (2020-06-27)
Chemical tools to monitor drug-target engagement of endogenously expressed protein kinases are highly desirable for preclinical target validation in drug discovery. Here, we describe a chemical genetics strategy to selectively study target engagement of endogenous kinases. By substituting a serine...
Qingfei Zheng et al.
The Journal of organic chemistry, 85(3), 1691-1697 (2019-12-26)
Methylglyoxal (MGO) is a reactive dicarbonyl metabolite that modifies histones in vivo and induces changes in chromatin structure and function. Here we report the synthesis and application of a chemical probe for investigating MGO-glycation. A two-step synthesis of a Cu-click...

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