The average molecular weight of this compound is 1,396 Da. There is no associated product datasheet for this item, however product C0926 is the identical material from another brand. Please see the link below to review the product datasheet for this item. This information applies to 778966 as well.
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/944/233/c0926pis.pdf
778966
(2-Hydroxypropyl)-β-cyclodextrin
Wacker Chemie AG
Synonym(s):
(2-Hydroxypropyl)-beta-cyclodextrin, Cavasol® W7 HP, HP-β-CD
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| Size/SKU | Availability | Price |
|---|---|---|
100 g | Available to ship TODAYfromMILWAUKEE | $363.00 |
500 g | Available to ship TODAYfromMILWAUKEE | $881.00 |
10 kg | Available to ship TODAYfromMILWAUKEE | $6,860.00 |
About This Item
Form:
powder
$363.00
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form
powder
Quality Segment
manufacturer/tradename
Wacker Chemie AG
extent of labeling
molar substitution per 0.60
impurities
≤1.0% unsubstituted cyclodextrin, ≤5.0% polypropylene glycol
ign. residue
≤2.5%
loss
≤7.0% loss on drying
SMILES string
CC(O)COCC1OC2OC3C(COCC(C)O)OC(OC4C(COCC(C)O)OC(OC5C(COCC(C)O)OC(OC6C(COCC(C)O)OC(OC7C(COCC(C)O)OC(OC8C(COCC(C)O)OC(OC1C(OCC(C)O)C2OCC(C)O)C(OCC(C)O)C8OCC(C)O)C(OCC(C)O)C7OCC(C)O)C(OCC(C)O)C6OCC(C)O)C(OCC(C)O)C5OCC(C)O)C(OCC(C)O)C4OCC(C)O)C(OCC(C)O)C3OCC(C)O
InChI
1S/C63H112O42/c1-22(64)8-85-15-29-50-36(71)43(78)57(92-29)100-51-30(16-86-9-23(2)65)94-59(45(80)38(51)73)102-53-32(18-88-11-25(4)67)96-61(47(82)40(53)75)104-55-34(20-90-13-27(6)69)98-63(49(84)42(55)77)105-56-35(21-91-14-28(7)70)97-62(48(83)41(56)76)103-54-33(19-89-12-26(5)68)95-60(46(81)39(54)74)101-52-31(17-87-10-24(3)66)93-58(99-50)44(79)37(52)72/h22-84H,8-21H2,1-7H3/t22?,23?,24?,25?,26?,27?,28?,29-,30-,31?,32?,33?,34?,35?,36?,37-,38?,39-,40+,41+,42+,43?,44+,45?,46+,47+,48+,49+,50+,51+,52-,53-,54-,55-,56-,57+,58-,59+,60-,61-,62-,63-/m1/s1
InChI key
ODLHGICHYURWBS-RYJYQAAZSA-N
General description
(2-Hydroxypropyl)- β -cyclodextrin (HP-β-CD), is a macrocyclic oligosaccharide with a hydrophobic inner cavity and a hydrophilic outer surface, that allows it to incorporate hydrophobic drugs into the cavities, thus enhancing water solubility and bioavailability of poorly water-soluble drugs. It also possesses high surface activity and stabilizing performance.
Application
2-Hydroxypropyl)-β-cyclodextrin is used as a:
- Macromolecular additive in the synthesis of single-phasetetragonal zirconium oxides.
- Precursor in the synthesis of polyrotaxane.
- Solubilizer and stabilizer in pharmaceutical formulations. HP-β-CD also shows potent anticancer activity.
The solubility of lipophilic drugs increases linearly with the concentration of hydroxypropyl-β-cyclodextrin (HBC) in aqueous solution because of the complex between HBC and the drug. This guest-host type complex is formed between the drug and the non-polar cavity in the HBC that results in enhanced solubility. Solutions may be lyophilized to produce freely soluble powders. Non-toxic in rabbits and mice.
Legal Information
Cavasol is a registered trademark of Wacker Chemie AG
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This Item | |||
|---|---|---|---|
| description Wacker Chemie AG | description powder | description average Mw ~1,540 | description average Mw ~1,460 |
| Quality Level 100 | Quality Level 300 | Quality Level 100 | Quality Level 200 |
| form powder | form powder | form powder | form powder |
| extent of labeling molar substitution per 0.60 | extent of labeling - | extent of labeling 1.0 molar substitution dextrin | extent of labeling 0.8 molar substitution |
| impurities ≤1.0% unsubstituted cyclodextrin, ≤5.0% polypropylene glycol | impurities - | impurities - | impurities - |
| manufacturer/tradename Wacker Chemie AG | manufacturer/tradename - | manufacturer/tradename - | manufacturer/tradename - |
| ign. residue ≤2.5% | ign. residue - | ign. residue - | ign. residue - |
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Storage Class
11 - Combustible Solids
flash_point_f
>752.0 °F
flash_point_c
> 400 °C
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Hello I'd like to know the molecular weight of this product. Thank you.
1 answer-
Helpful?
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Hi! I would like to know the purity of this HPBCD. I just saw the Beta Cyclodextrin specification has a >98% assay. Is that the same for HPBCD from this manufacturer?
1 answer-
The purity of this product is not determined. However, there are specifications set for certain impurities, as well as moisture content. Please see the link below to review these specifications:
https://www.sigmaaldrich.com/US/en/specification-sheet/ALDRICH/778966
If a quantitative purity is required, please see product H107 which has a minimum purity specification of 98%:
https://www.sigmaaldrich.com/US/en/product/sigma/h107Helpful?
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