MilliporeSigma
  • 779229
All Photos(1)

779229

Sigma-Aldrich

(2-Hydroxypropyl)-γ-cyclodextrin

Produced by Wacker Chemie AG, Burghausen, Germany, Life Science

Synonym(s):
Cavasol® W8 HP, HGC
CAS Number:
NACRES:
NA.22

grade

Produced by Wacker Chemie AG, Burghausen, Germany, Life Science

Quality Level

form

powder

extent of labeling

0.5-0.7 molar substitution

impurities

≤0.1% propylene glycol (Ph Eur)

loss

≤10.0% loss on drying

pH

6-9 (2% in H2O)

InChI

1S/C51H88O38/c1-14(56)8-73-11-21-42-29(64)36(71)50(81-21)85-40-19(6-54)79-48(34(69)27(40)62)89-44-23(13-75-10-16(3)58)82-51(37(72)30(44)65)86-41-20(7-55)78-47(33(68)26(41)61)88-43-22(12-74-9-15(2)57)80-49(35(70)28(43)63)84-39-18(5-53)76-45(31(66)24(39)59)83-38-17(4-52)77-46(87-42)32(67)25(38)60/h14-72H,4-13H2,1-3H3/t14?,15?,16?,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-/m0/s1

InChI key

ODLHGICHYURWBS-RYJYQAAZSA-N

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

1 of 4

This Item
W402826C0926778907
β-Cyclodextrin produced by Wacker Chemie AG, Burghausen, Germany

Sigma-Aldrich

W402826

β-Cyclodextrin

form

powder

form

powder

form

powder

form

powder

Quality Level

200

Quality Level

400

Quality Level

200

Quality Level

100

grade

Produced by Wacker Chemie AG, Burghausen, Germany, Life Science

grade

produced by Wacker Chemie AG, Burghausen, Germany

grade

-

grade

Produced by Wacker Chemie AG, Burghausen, Germany, Life Science

extent of labeling

0.5-0.7 molar substitution

extent of labeling

-

extent of labeling

4-10 (determined by NMR)

extent of labeling

0.59-0.73 molar substitution

impurities

≤0.1% propylene glycol (Ph Eur)

impurities

-

impurities

-

impurities

≤0.1% related substances, any (Ph Eur), ≤0.5% propylene glycol (Ph Eur), ≤1.0% β-dex (Ph Eur), ≤1.0% related substances, total other, ≤1.0 ppm propylene oxide

loss

≤10.0% loss on drying

loss

-

loss

-

loss

≤10.0% loss on drying

General description

(2-Hydroxypropyl)-γ-cyclodextrin (HP-β-CD) is a hydrophilic compound that can be used as a complexing agent to increase the aqueous solubility and dissolution rate of the drug molecule.

Application

For R&D use
HP-β-CD can be utilized to improve the aqueous solubility and dissolution rate of zolpidem (ZP) upon complexation. ZP-HP-β-CD complexes showed improved ataxic activity.
It is also used to enhance the wound healing property of curcumin by increasing the water solubility.

Legal Information

Cavasol is a registered trademark of Wacker Chemie AG

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

(enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service