791040

Sigma-Aldrich

Zinc n-propylsulfinate

95% (H-NMR)

Synonym(s):
Bis[(propylsulfinyl)oxy]zinc, Baran NPS Reagent
Empirical Formula (Hill Notation):
C6H14O4S2Zn
CAS Number:
Molecular Weight:
279.69
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

95% (H-NMR)

reaction suitability

reaction type: C-C Bond Formation
reagent type: catalyst
reaction type: C-H Activation

mp

80-105 °C

storage temp.

2-8°C

SMILES string

CCCS(O[Zn]OS(CCC)=O)=O

InChI

1S/2C3H8O2S.Zn/c2*1-2-3-6(4)5;/h2*2-3H2,1H3,(H,4,5);/q;;+2/p-2

InChI key

AVEWLRYVGNMIHD-UHFFFAOYSA-L

Application

Zinc n-propylsulfinate (NPS) is part of a zinc sulfinate toolbox developed by Phil Baran for the simple and rapid diversification of heterocycles.


Learn More at the
Professor and Product Portal of Professor Phil S. Baran.

Practical and Innate Carbon-Hydrogen Functionalization of Heterocycles

Packaging

1 g in glass bottle

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Yuta Fujiwara et al.
Nature, 492(7427), 95-99 (2012-12-04)
Nitrogen-rich heterocyclic compounds have had a profound effect on human health because these chemical motifs are found in a large number of drugs used to combat a broad range of diseases and pathophysiological conditions. Advances in transition-metal-mediated cross-coupling have simplified...
Fionn O'Hara et al.
Journal of the American Chemical Society, 135(32), 12122-12134 (2013-07-19)
Radical addition processes can be ideally suited for the direct functionalization of heteroaromatic bases, yet these processes are only sparsely used due to the perception of poor or unreliable control of regiochemistry. A systematic investigation of factors affecting the regiochemistry...
Articles
The synthesis of heteroaromatic and aromatic compounds is at the heart of the chemical industry. The ever-growing demand for new chemical entities, coupled with dwindling resources and time constraints allotted to any given research project, a rapid way to diversify (hetero)aromatic scaffolds is needed.
Read More

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