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MilliporeSigma

797928

Sigma-Aldrich

Fluorescent silica nanobeads

25 nm, lyophilized

Synonym(s):

Fluorescent beads, Fluorescent nanoparticles, Silica nanoparticles

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5 MG
$632.00

$632.00


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About This Item

Linear Formula:
SiO2
Molecular Weight:
60.08
UNSPSC Code:
12352302
NACRES:
NA.23

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Quality Level

form

powder

particle size

25 nm

fluorescence

λem 590 nm

UV absorption

λ: 570 nm Amax

storage temp.

2-8°C

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Application

The use of labeling or staining agents has greatly assisted the study of complex biological interactions in biology and the fluorescent labeling of biomolecules has been demonstrated as an indispensable tool in many biological studies. By virtue of excellent fluorescence properties the silica nanobeads find application in biological labeling, bioimaging, biosensing etc.[1][2]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Geometrical confinement of quantum dots in porous nanobeads with ultraefficient fluorescence for cell-specific targeting and bioimaging
P-J Chen, S-H Hu, W-T Hung, S-Y Chen, and D-M Liu,
Journal of Materials Chemistry, 22(19), 9568-9575 (2012)
Luminescent nanomaterials for biological labelling
F. Wang, W. B. Tan, Y. Zhang, et al.
Nanotechnology, 17(1), R1-R13 (2006)

Articles

RAFT polymerization controls chain growth, yields defined polymers without cytotoxic heavy metals like ATRP.

Biomaterials science integrates smart materials into biological research, requiring a deep understanding of biological systems.

Questions

1–3 of 3 Questions  
  1. Are they water soluble or we need to use dmso or other organic solvents?

    1 answer
    1. These nanobeads are soluble in water. There are -OH groups present on the bead surface. The excitation and emission spectra are shown below.

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  2. what type of amorphous silica is this (i.e. colloidal, fumed, fused, etc..)

    1 answer
    1. The particles are highly monodispersed, but the method of synthesis is proprietary to the manufacturer.

      Helpful?

  3. Are they stable in high ionic strength buffers?

    1 answer
    1. These nanobeads are negatively charged in water. Alkaline solutions, such as ammonia, may improve stability. The stability in a high ionic strength buffer would depend on the specific components, but most often would not enhance the stability.

      To discuss this further, we kindly ask you to navigate to the link https://www.sigmaaldrich.com/techservice and click on "Product Technical Inquires" under the Products Section with all the required information so that a member of our team can reach out to you to assist further. Thank you.

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