Line S Tarpgaard et al.
BMC cancer, 16, 91-91 (2016-02-13)
The overall purpose of this study is to provide proof of concept for introducing the anthracycline epirubicin as an effective, biomarker-guided treatment for metastatic colorectal cancer (mCRC) patients who are refractory to treatment with oxaliplatin-based chemotherapy and have TOP2A gene...
Inkjet-Printed Flexible Graphene-Based Supercapacitor.
Matthew E, et al.
Electrochimica Acta, 147, 610-616 (2014)
Zhiyong Liang et al.
BMC cancer, 8, 363-363 (2008-12-09)
The EGFR and HER2 genes are located on chromosomes 7 and 17, respectively. They are therapeutic targets in some tumors. The TOP2A gene, which is located near HER2 on chromosome 17, is the target of many chemotherapeutic agents, and co-amplification...
A M Bofin et al.
Cytopathology : official journal of the British Society for Clinical Cytology, 14(6), 314-319 (2003-11-25)
The TOP2A gene is located on chromosome 17 close to the HER-2 gene. It encodes an enzyme involved in the regulation of cell proliferation. Using fluorescence in situ hybridization (FISH), we have examined fine needle aspiration smears from 42 cases...
Mahesh Ramamoorthy et al.
Nucleic acids research, 40(4), 1621-1635 (2011-10-21)
DNA decatenation mediated by Topoisomerase II is required to separate the interlinked sister chromatids post-replication. SGS1, a yeast homolog of the human RecQ family of helicases interacts with Topoisomerase II and plays a role in chromosome segregation, but this functional...