809926

Sigma-Aldrich

1α,25-Dihydroxyvitamin D3-26,26,26,27,27,27-d6 solution

100 μg/mL in ethanol, ≥98 atom % D, ≥95% (CP)

Empirical Formula (Hill Notation):
C27D6H38O3
CAS Number:
Molecular Weight:
422.67
EC Number:
PubChem Substance ID:
NACRES:
NA.12

Quality Level

isotopic purity

≥98 atom % D

assay

≥95% (CP)

form

liquid

concentration

100 μg/mL in ethanol

application(s)

mass spectrometry (MS): suitable

color

colorless

mass shift

M+6

storage temp.

−20°C

SMILES string

C=C1[C@@H](O)C[C@H](O)C/C1=C/C=C2C(CCC3[C@H](C)CCCC(O)(C([2H])([2H])[2H])C([2H])([2H])[2H])[C@]3(C)CCC/2

InChI

1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23?,24?,25+,27-/m1/s1/i3D3,4D3

InChI key

GMRQFYUYWCNGIN-LPTLAYIMSA-N

Related Categories

General description

1α,25-Dihydroxyvitamin D3 [1,25(OH)2D3], also known as calcitriol, plays a role in calcium and phosphate metabolism in humans. It also regulates insulin secretion and induces cellular differentiation.
1α,25-Dihydroxyvitamin D3-26,26,26,27,27,27-d6 is a deuterated vitamin D3 wherein C-26 and C-27 carbon methyl protons are replaced by deuterium.

Application

1α,25-Dihydroxyvitamin D3-26,26,26,27,27,27-d6 can be used as an analytical standard for the quantitative analysis of dihydroxyvitamin D3 concentration in human serum via LC-MS.

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Precautionary Statements

RIDADR

UN1170 - class 3 - PG 2 - Ethanol, solution

WGK Germany

WGK 1

Flash Point(F)

57.2 °F

Flash Point(C)

14 °C

Certificate of Analysis
Certificate of Origin
Quantification of 1, 25-dihydroxyvitamin D2 and D3 in serum using liquid chromatography-tandem mass spectrometry
Clinical Applications of Mass Spectrometry in Biomolecular Analysis, 63(2), 291-300 (2016)
Paola Illesca et al.
Food & function, 11(10), 9086-9102 (2020-10-08)
Nutritional interventions are promising tools for the prevention of obesity. The n-3 long-chain polyunsaturated fatty acid (n-3 LCPUFA) docosahexaenoic acid (DHA) modulates immune and metabolic responses while the antioxidant hydroxytyrosol (HT) prevents oxidative stress (OS) in white adipose tissue (WAT)....
The emerging role of vitamin D3 in women′s health
Khadilkar, SS
The Journal of Obstetrics and Gynecology of India, 63(2), 147?150-147?150 (2013)
Vitamin D3: a helpful immuno-modulator
Di R, et al.
Immunology, 134(2), 123-139 (2011)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.