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81300

Sigma-Aldrich

Poly(ethylene glycol)

average Mn 20,000

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Synonym(s):
PEG
Linear Formula:
H(OCH2CH2)nOH
CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.23

form

flakes

Quality Level

mol wt

average Mn 20,000

mp

63-66 °C

Ω-end

hydroxyl

α-end

hydroxyl

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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1 of 4

This Item
8126081310P2139
Poly(ethylene glycol) average Mn 20,000

Sigma-Aldrich

81300

Poly(ethylene glycol)

Poly(ethylene glycol) average Mn 6,000

Sigma-Aldrich

81260

Poly(ethylene glycol)

Poly(ethylene glycol) 35,000

Sigma-Aldrich

81310

Poly(ethylene glycol)

Poly(ethylene glycol) average mol wt 8,000, powder

Sigma-Aldrich

P2139

Poly(ethylene glycol)

mol wt

average Mn 20,000

mol wt

Mn 5,000-7,000, average Mn 6,000

mol wt

average Mn 35,000

mol wt

average mol wt 8,000

mp

63-66 °C

mp

60-63 °C

mp

64-66 °C

mp

-

Ω-end

hydroxyl

Ω-end

hydroxyl

Ω-end

hydroxyl

Ω-end

hydroxyl

α-end

hydroxyl

α-end

hydroxyl

α-end

hydroxyl

α-end

hydroxyl

Quality Level

200

Quality Level

300

Quality Level

200

Quality Level

200

General description

Polyethylene glycol (PEG) is a hydrophilic polymer. It can be easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups. When crosslinked into networks PEG can have high water content, forming “hydrogels”. Hydrogel formation can be initiated by either crosslinking PEG by ionizing radiation or by covalent crosslinking of PEG macromers with reactive chain ends. PEG is a suitable material for biological applications because it does not trigger an immune response.

Application

PEG has been used to modify therapeutic proteins and peptides to increase their solubility and lower their toxicity.

Photopolymerized PEG hydrogels have emerging applications in the fabrication of bioactive and immunoisolating barriers for encapsulation of cells.

Other Notes

Molecular weight: Mn 16,000-24,000

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Articles

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds via Bio-orthogonal Click Reactions

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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