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81381

Sigma-Aldrich

Mowiol® 4-88

Mw ~31,000

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Synonym(s):
Poly(vinyl alcohol)
Linear Formula:
[-CH2CHOH-]n
CAS Number:
MDL number:
NACRES:
NA.23

form

crystals

Quality Level

mol wt

Mw ~31,000

extent of labeling

86.7-88.7 mol% hydrolysis
~630 polymerization

ign. residue

≤0.5%

viscosity

3.5-4.5 mPa.s, 4 % in H2O(20 °C)

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

InChI key

IMROMDMJAWUWLK-UHFFFAOYSA-N

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1 of 4

This Item
813838136581382
vibrant-m

81381

Mowiol® 4-88

vibrant-m

81383

Mowiol® 8-88

vibrant-m

81365

Mowiol® 18-88

vibrant-m

81382

Mowiol® 4-98

mol wt

Mw ~31,000

mol wt

Mw ~67,000

mol wt

Mw ~130,000

mol wt

Mw ~27,000

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

viscosity

3.5-4.5 mPa.s, 4 % in H2O(20 °C)

viscosity

7-9 mPa.s, 4 % in H2O(20 °C)

viscosity

16-20 mPa.s, 4 % in H2O(20 °C)

viscosity

4-5 mPa.s, 4 % in H2O(20 °C)

extent of labeling

86.7-88.7 mol% hydrolysis

extent of labeling

86.7-88.7 mol% hydrolysis, ~1,400 polymerization

extent of labeling

86.7-88.7 mol% hydrolysis, ~2,700 polymerization

extent of labeling

98.0-98.8 mol% hydrolysis, ~600 polymerization

ign. residue

≤0.5%

ign. residue

≤0.5%

ign. residue

≤0.5%

ign. residue

≤0.5%

General description

Mowiol® is a water soluble hydrocolloid mucoadhesive based on poly (vinyl alcohol). Mowiol® at pH 8.5 has a couple of advantages over other mounting media:
  • its a liquid when the sample is mounted and solidifies after several hours, forming a permanent bond between the coverslip and slide
  • fluorescence is stable when held in dark and at 4oC.

Application

Mowiol® is used as an embedding medium for preserving stained cell dishes in the study of siRNA array production of HeLa cells. Mowiol® is also reported to be used as a mounting medium in:
  • design of TSAR and its applications
  • detection of the secreted and cytoplasmic fractions of IpaB, IpaC and IpaD by lysozyme permeabilization
  • fluorescence recovery after photobleaching (FRAP).

Mowiol® may be used as a coating for sensors based on piezoelectric quartz crystals. Another probable use of Mowiol® is during the study of super fluorescence imaging of biocompatible carbon dots.

Legal Information

Mowiol is a registered trademark of Kuraray Europe GmbH

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

No data available

flash_point_c

No data available

ppe

Eyeshields, Gloves, type N95 (US)


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Xiaofang Li et al.
Scientific reports, 7(1), 16495-16495 (2017-12-01)
Heterogeneity in terms of tumor characteristics, prognosis, and survival among cancer patients is an unsolved issue. Here, we systematically analyzed the aberrant expression patterns of cervical cancer using RNA-Seq data from The Cancer Genome Atlas (TCGA). We incorporated gene profiling
Avgi Tsolou et al.
Life sciences, 232, 116562-116562 (2019-06-16)
Lung cancer is one of the main causes of cancer-related deaths worldwide and radiotherapy is a major treatment of choice. However, radioresistance is a main reason for radiotherapy failure or tumor relapse. Here, we investigated possible mechanisms associated with cancer
Super-resolution fluorescence imaging of biocompatible carbon dots.
Lemenager G, et al.
Nanoscale, 6, 8614-8623 (2014)
Cedric S Tremblay et al.
Nature communications, 9(1), 3535-3535 (2018-09-01)
Pre-leukemic stem cells (pre-LSCs) give rise to leukemic stem cells through acquisition of additional gene mutations and are an important source of relapse following chemotherapy. We postulated that cell-cycle kinetics of pre-LSCs may be an important determinant of clonal evolution
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