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855642

Sigma-Aldrich

N-Acetyl-L-glutamic acid

ReagentPlus®, 99%

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Synonym(s):
(2S)-2-Acetamidopentanedioic acid, N-Acetylglutamic acid
Linear Formula:
HO2CCH2CH2CH(NHCOCH3)CO2H
CAS Number:
Molecular Weight:
189.17
Beilstein/REAXYS Number:
1727473
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22

Quality Level

product line

ReagentPlus®

assay

99%

form

powder

optical activity

[α]22/D −15.6°, c = 1 in H2O

reaction suitability

reaction type: solution phase peptide synthesis

mp

194-196 °C (lit.)

application(s)

peptide synthesis

storage temp.

2-8°C

SMILES string

CC(=O)N[C@@H](CCC(O)=O)C(O)=O

InChI

1S/C7H11NO5/c1-4(9)8-5(7(12)13)2-3-6(10)11/h5H,2-3H2,1H3,(H,8,9)(H,10,11)(H,12,13)/t5-/m0/s1

InChI key

RFMMMVDNIPUKGG-YFKPBYRVSA-N

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1 of 4

This Item
C4375G1251P0380
vibrant-m

855642

N-Acetyl-L-glutamic acid

vibrant-m

C4375

N-Carbamyl-L-glutamic acid

vibrant-m

G1251

L-Glutamic acid

vibrant-m

P0380

L-Proline

form

powder

form

powder

form

powder

form

powder

assay

99%

assay

≥98.0% (TLC)

assay

≥99% (HPLC)

assay

≥99% (HPLC)

mp

194-196 °C (lit.)

mp

-

mp

205 °C (dec.) (lit.)

mp

228 °C (dec.) (lit.)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

-

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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W Zhang et al.
Clinical and investigative medicine. Medecine clinique et experimentale, 13(4), 183-188 (1990-08-01)
Liver tissue from 3 patients with carbamyl phosphate synthetase I deficiency and 11 patients with ornithine transcarbamylase deficiency was analyzed by Western blots for the presence of carbamyl phosphate synthetase I and ornithine transcarbamylase cross-reactive material with anti-rat enzyme antibodies.
Jiguang Wang et al.
Poultry science, 99(7), 3583-3593 (2020-07-04)
The present study determined the effects of in ovo feeding (IOF) of N-acetyl-L-glutamate (NAG) on early intestinal development and growth performance of broilers. A total of 702 fertile broiler eggs were randomly divided into 3 treatments: 1) non-punctured control group
M Tuchman et al.
Pediatric research, 27(4 Pt 1), 408-412 (1990-04-01)
N-acetylglutamate (NAG) content was measured in homogenates of liver and small intestine obtained from normal and 24-h starved syngeneic mice. Subsequently, NAG was determined in normal, and in carbamyl phosphate synthetase I and ornithine transcarbamylase enzyme-deficient human liver tissue homogenates.
J Vockley et al.
Biochemical medicine and metabolic biology, 47(1), 38-46 (1992-02-01)
N-Acetyl-L-glutamate synthetase (NAG synthetase) is a mitochondrial matrix enzyme which catalyzes the synthesis of N-acetyl-Lglutamate (NAG), a physiologic activator of the urea cycle enzyme carbamylphosphate synthetase I. Deficiency of NAG synthetase in humans has been reported only three times previously.
K Sugahara et al.
Journal of chromatography. B, Biomedical applications, 657(1), 15-21 (1994-07-01)
Liquid chromatography-atmospheric pressure chemical-ionization mass spectrometry (LC-APCI-MS) was used for the analysis of N-acetylamino acids that could not be determined with an amino acid analyzer. LC-APCI-MS could directly detect the protonated molecular ions of various synthetic N-acetylamino acids, distinguishing N-acetylserine

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