857335

(1S,2R)-(+)-Ephedrine hydrochloride

99%

• Synonym(s): (1S,2R)-(+)-α-(1-Methylaminoethyl)benzyl alcohol hydrochloride, (1S,2R)-(+)-2-Methylamino-1-phenyl-1-propanol hydrochloride, D-α-(1-Methylaminoethyl)benzyl alcohol hydrochloride
• Linear Formula: C₆H₅CH[CH(NHCH₃)CH₃]OH · HCl
• CAS Number: 24221-86-1
• Molecular Weight: 201.69
• Beilstein/REAXYS Number: 6118541
• EC Number: 246-090-7
• MDL number: MFCD00064551
• UNSPSC Code: 12352116
• PubChem Substance ID: 24888441
• NACRES: NA.22

Properties

• assay: 99%
• form: crystals
• optical activity: [α]23/D +34.3°, c = 5 in H₂O
• mp: 218-220 °C (lit.)
• SMILES string: Cl[H].CN[C@H](C)[C@@H](O)c1ccccc1
• InChI: 1S/C10H15NO.ClH/c1-8(11-2)10(12)9-6-4-3-5-7-9;/h3-8,10-12H,1-2H3;1H/t8-,10-;/m1./s1
• InChI key: BALXUFOVQVENIU-GHXDPTCOSA-N

Description

General description

Ephedrines are quite significant components in asymmetric synthesis; they are commonly used as key components in the preparation of heterocyclic compounds. They are also used as reagents/ catalytic substances or ligands for the synthesis of aryl/heteroaryl derivatives and organometallic complexes.[1][2][3]

Application

(1S,2R)-(+)-Ephedrine hydrochloride may be used in the preparation of (R)-methcathinone via permanganate method of oxidation.[4]

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable