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Sigma-Aldrich

(1S,2R)-(+)-Ephedrine hydrochloride

99%

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Synonym(s):
(1S,2R)-(+)-α-(1-Methylaminoethyl)benzyl alcohol hydrochloride, (1S,2R)-(+)-2-Methylamino-1-phenyl-1-propanol hydrochloride, D-α-(1-Methylaminoethyl)benzyl alcohol hydrochloride
Linear Formula:
C6H5CH[CH(NHCH3)CH3]OH · HCl
CAS Number:
Molecular Weight:
201.69
Beilstein:
6118541
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

99%

form

crystals

optical activity

[α]23/D +34.3°, c = 5 in H2O

mp

218-220 °C (lit.)

SMILES string

Cl[H].CN[C@H](C)[C@@H](O)c1ccccc1

InChI

1S/C10H15NO.ClH/c1-8(11-2)10(12)9-6-4-3-5-7-9;/h3-8,10-12H,1-2H3;1H/t8-,10-;/m1./s1

InChI key

BALXUFOVQVENIU-GHXDPTCOSA-N

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This Item
862231134910317500
form

crystals

form

crystals

form

solid

form

solid

optical activity

[α]23/D +34.3°, c = 5 in H2O

optical activity

[α]20/D −34°, c = 4 in H2O

optical activity

[α]21/D −41°, c = 5 in 1 M HCl

optical activity

[α]20/D +40°, c = 7 in 1 M HCl

mp

218-220 °C (lit.)

mp

216-220 °C (lit.)

mp

37-39 °C (lit.)

mp

51-54 °C (lit.)

General description

Ephedrines are quite significant components in asymmetric synthesis; they are commonly used as key components in the preparation of heterocyclic compounds. They are also used as reagents/ catalytic substances or ligands for the synthesis of aryl/heteroaryl derivatives and organometallic complexes.

Application

(1S,2R)-(+)-Ephedrine hydrochloride may be used in the preparation of (R)-methcathinone via permanganate method of oxidation.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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