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901756

Low endotoxin gelatin from porcine skin

gel strength 240-360 (Bloom), <10 EU/g Endotoxin

Synonym(s):

beMatrix gelatin LS-H, Gelatin / GelMA & derivatives

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1 g

Estimated to ship TODAYfromMILWAUKEE

$688.00
5 g

Estimated to ship TODAYfromMILWAUKEE

$688.00

About This Item

CAS Number:
MDL number:
NACRES:
NA.23
UNSPSC Code:
41116130

$688.00


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form

powder

impurities

<10 EU/g Endotoxin, <300 g Total viable aerobic count

loss

<15% loss on drying

color

white to pale yellow

pH

5.0-6.5

viscosity

4.0-6.5 mPa.s

anion traces

sulfite (SO32-): <1.5 mg/20g

cation traces

As: <1 ppm, Hg: <0.1 ppm, heavy metals: <20 ppm

Application

Gelatin has received significant attention in the biomedical field due to its inherent bioactivity. Low endotoxin gelatin from porcine skin, gel strength 300 bloom is a high bloom (high molecular weight) gelatin featuring less than 10 endotoxin units (EU) per gram[1]. Endotoxins primarily consist of lipopolysaccharides from the outer membrane of gram-negative bacteria. Once in the bloodstream, endotoxins are capable of eliciting a strong immune response, potentially leading to fever, shock, a drop in blood pressure, and even potentially death[2][3]. In addition to this immune response, several reports suggest endotoxins may also damage various types of cells[4][5][6][7]. To avoid adverse effects, raw materials should contain the lowest level of endotoxins possible when used in biomedical or regenerative medicine research applications. This low endotoxin gelatin is derived from alkaline-treated porcine skin and has a variety of potential applications in the fields of regenerative medicine, medical devices, and tissue engineering research.

Legal Information

beMatrix is a trademark of Nitta Gelatin

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This Item
920010920037G2625
form

powder

form

powder

form

powder

form

powder

impurities

<10 EU/g Endotoxin, <300 g Total viable aerobic count

impurities

≤10 EU/g Endotoxin

impurities

≤10 EU/g Endotoxin

impurities

-

color

white to pale yellow

color

white to off-white

color

white to off-white

color

-

cation traces

As: <1 ppm, heavy metals: <20 ppm, Hg: <0.1 ppm

cation traces

-

cation traces

-

cation traces

-

loss

<15% loss on drying

loss

-

loss

-

loss

-

pH

5.0-6.5

pH

-

pH

-

pH

-


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Storage Class

11 - Combustible Solids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable



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K W Brunson et al.
Journal of supramolecular structure, 9(2), 231-242 (1978-01-01)
Chinese hamster ovary (CHO . K1 . PRO) cell growth was inhibited by addition of a gram-negative bacterial lipopolysaccharide (LPS) to the cell culture medium. Growth inhibition began after three or four days of incubation, was dose-dependent up to a
J M Harlan et al.
Laboratory investigation; a journal of technical methods and pathology, 48(3), 269-274 (1983-03-01)
Lipopolysaccharide (LPS) produced time- and dose-dependent bovine endothelial cell injury in vitro that was manifested initially by cell detachment from culture substrate with subsequent cell lysis. Bovine endothelial cell injury was observed with LPS derived from Salmonella minnesota R595, a
E J Ziegler et al.
The New England journal of medicine, 307(20), 1225-1230 (1982-11-11)
In an effort to decrease deaths from gram-negative bacteremia and endotoxin shock, we treated bacteremic patients with human antiserum to endotoxin (lipopolysaccharide) core. Antiserum was prepared by vaccinating healthy men with heat-killed Escherichia coli J5; this mutant lacks lipopolysaccharide oligosaccharide



Global Trade Item Number

SKUGTIN
967100102504022536500980
901756-5G04061834898429
901756-1G04061834898412

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