Tris(dimethylamino)sulfonium bifluoride

greener alternative
(Me2N)3S+[FHF], Bifluoride salt SuFEx catalyst
Empirical Formula (Hill Notation):
CAS Number:
Molecular Weight:


powder or solid

reaction suitability

reagent type: catalyst
reaction type: Fluorinations

greener alternative product characteristics

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storage temp.


General description

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Bifluoride salt reported by K. Barry Sharpless and colleagues as a powerful catalyst for the sulfur(VI) fluoride exchange (SuFEx) reaction between aryl silyl ethers and aryl fluorosulfates or alkyl sulfonyl fluorides. Superior to organosuperbases DBU and BEMP, tris(dimethylamino)sulfonium bifluoride enables low catalyst loading (0.05 mol%) for preparation of polysulfates and polysulfonates with high molecular weight and narrow polydispersity. Reaction is amenable to scale up.


NONH for all modes of transport

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Hua Wang et al.
Angewandte Chemie (International ed. in English), 56(37), 11203-11208 (2017-08-10)
The SuFEx-based polycondensation between bisalkylsulfonyl fluorides (AA monomers) and bisphenol bis(t-butyldimethylsilyl) ethers (BB monomers) using [Ph
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