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909874

Sigma-Aldrich

N-Hydroxysuccinimide ester-poly(ethylene glycol)-b-poly(D,L lactide)

PEG average Mn 5,000, PDLA average Mn 16,000

Synonym(s):

NHS ester PEG-PDLA, NHS ester PEG-PLA, NHS-PEG-PDLA, NHS-PEG-PLA

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100 MG
$297.35

About This Item

Linear Formula:
HO(C3H4O2)m(C2H4O)nC7H8NO4
UNSPSC Code:
12352005
NACRES:
NA.23

$297.35

List Price$313.00
Web-Only Promotion

In StockDetails


Request a Bulk Order

form

powder or chunks

mol wt

PDLA average Mn 16,000 (by NMR)
PEG average Mn 5,000 (by NMR)

color

white to tan

storage temp.

−20°C

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This Item
901841902241900656
form

powder or chunks

form

powder or solid

form

powder

form

solid

mol wt

PDLA average Mn 16,000 (by NMR), PEG average Mn 5,000 (by NMR)

mol wt

PCL average Mn 5,000, PEG average Mn 5,000

mol wt

PEG Mn 4000-6000 g/mol (by NMR), PEG average Mn 5000, PLGA Mn 13500-16500 g/mol (by NMR), PLGA average Mn 15000

mol wt

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

color

white to tan

color

white to off-white

color

white

color

-

Application

N-Hydroxysuccinimide ester-poly(ethylene glycol)-b-poly(D,L lactide) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLA block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). The NHS functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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