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911186

Poly(ethylene glycol) linear dendrimer

carboxyl terminated, PEG Mn 10K, generation 5

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500 MG

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About This Item

Empirical Formula (Hill Notation):
C1020H1662O606
Molecular Weight:
23621.75
NACRES:
NA.23
UNSPSC Code:
12162002

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Product Name

Poly(ethylene glycol) linear dendrimer, carboxyl terminated, PEG Mn 10K, generation 5

form

solid

mol wt

PEG Mn 10K
PEG average Mn 10,000
generation 5

no. Surface Groups

64

functional group

carboxylic acid

color

white to off-white

storage temp.

−20°C

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1 of 4

This Item
911364901397911496
Poly(ethylene glycol) linear dendrimer carboxyl terminated, PEG Mn 10K, generation 5

Sigma-Aldrich

911186

Poly(ethylene glycol) linear dendrimer

Poly(ethylene glycol) linear dendrimer carboxyl terminated, PEG Mn 10k, generation 4

Sigma-Aldrich

911364

Poly(ethylene glycol) linear dendrimer

Poly(ethylene glycol) linear dendrimer NHBoc terminated, PEG Mn 6000, generation 4

Sigma-Aldrich

901397

Poly(ethylene glycol) linear dendrimer

Polyester bis-MPA dendron, 4 carboxyl, 1 Rhodamine (core) generation 2

Sigma-Aldrich

911496

Polyester bis-MPA dendron, 4 carboxyl, 1 Rhodamine (core)

form

solid

form

solid

form

solid

form

solid

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

mol wt

PEG Mn 10K

mol wt

PEG Mn 10k, PEG average Mn 10,000, generation 4

mol wt

PEG Mn 6000

mol wt

generation 2

no. Surface Groups

64

no. Surface Groups

32

no. Surface Groups

-

no. Surface Groups

4

color

white to off-white

color

white to off-white

color

white to off-white

color

red to pink

functional group

carboxylic acid

functional group

carboxylic acid

functional group

-

functional group

(Rhodamine(core))

General description

  • Polymer architecture: PEG-core dendrimer
  • Bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid

Application

Bis-MPA dendritic molecules are based on 2,2-bismethylolpropionicacid (bis-MPA) building blocks. The hydrolyzable linker allows for degradation into byproducts that can be reabsorbed by the body or into excretable non-toxic small molecules. This dendritic polymer is biocompatible, biodegradable, and suitable for biomedical applications. PEG-core dendrimers feature excellent solubility in water and a high degree of functionality per PEG chain, enable use for advanced drug delivery systems or for drug targeting. The carboxylic acid-functionalized corona can be readily used for bioconjugation reactions.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ6262
MKCL6596

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Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications
Garcia-Gallego S, et al
Progress in Polymer Science, 48, 85?110-85?110 (2015)
Anna Carlmark et al.
Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been

Articles

Dendritic Polyester Scaffolds for Drug Delivery

Dendritic molecules' biomedical applications, particularly bis-MPA dendritic scaffolds, hold promise for drug delivery.

New Multi-Dendrimer Platforms for Supramolecular Assembly

Dendrimers, polymer nanostructures, are synthesized for specific purposes by manipulating critical nanoscale design parameters (CNDPs).

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