Polyester bis-MPA dendron, 2 NHBoc, 1 NHS (core)

Name: Polyester bis-MPA dendron, 2 NHBoc, 1 NHS (core)
Brand: ALDRICH
Price: 2120 USD

generation 1

Synonym(s):

Bis-MPA dendron, NHS-NHBoc dendron

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About This Item

Empirical Formula (Hill Notation):

C₂₅H₃₉N₃O₁₂

Molecular Weight:

573.59

UNSPSC Code:

12162002

NACRES:

NA.23

Key Documents

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description

NHBoc, 1 NHS (core)

form

solid or liquid

mol wt

generation 1

no. Surface Groups

color

colorless to white

functional group

(NHS(core))

storage temp.

−20°C

Related Categories

Biomedical Materials

Biomedical Polymers

Materials Science

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1 of 4

This Item	911488	911577	901332
Sigma-Aldrich 911461 Polyester bis-MPA dendron, 2 NHBoc, 1 NHS (core)	Sigma-Aldrich 911488 Polyester bis-MPA dendron, 4 NHBoc	Sigma-Aldrich 911577 Polyester bis-MPA dendron 2 NHBoc, 1 Biotin (core)	Sigma-Aldrich 901332 Polyester bis-MPA dendron 8 NHBoc, 1 azide (core)
form solid or liquid	form solid (Viscous)	form solid (Viscous)	form solid
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
description NHBoc, 1 NHS (core)	description -	description 2 NHBoc, 1 Biotin (core)	description 8 NHBoc, 1 azide (core)
mol wt generation 1	mol wt generation 2	mol wt generation 1	mol wt generation 3
no. Surface Groups 2	no. Surface Groups 4	no. Surface Groups 2	no. Surface Groups 8
color colorless to white	color colorless to white	color colorless to white	color white to off-white

General description

Polymer architecture: Dendron
End Group Functionality: NHBoc
Bis-MPA : 2,2-bis(hydroxymethyl)propionic acid

Application

Bis-MPA dendritic molecules are based on 2,2-bismethylolpropionicacid (bis-MPA) building blocks. The hydrolysable linkers presented in this type of polymers allows their degradation into byproducts that can be reabsorbed by the body or into excretable non-toxic small molecules. Therefore, this group of dendritic polymers are biocompatible and biodegradable, making them suitable for biomedical applications. The NHBoc-functionalized corona and NHS-functionalized core of this product can be readily used in bioconjugation reactions.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

MKCM2815

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Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications.

Garcia-Gallego S, et al

Progress in Polymer Science, 48, 85-110 (2015)

Dendritic architectures based on bis-MPA: functional polymeric scaffolds for application-driven research.

Anna Carlmark et al.

Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)

Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been

Articles

Dendritic Polyester Scaffolds for Drug Delivery

Dendritic molecules' biomedical applications, particularly bis-MPA dendritic scaffolds, hold promise for drug delivery.

New Multi-Dendrimer Platforms for Supramolecular Assembly

Dendrimers, polymer nanostructures, are synthesized for specific purposes by manipulating critical nanoscale design parameters (CNDPs).

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Polyester bis-MPA dendron, 2 NHBoc, 1 NHS (core)