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911690

C5 Lenalidomide

≥95%

Synonym(s):

3-(5-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione, E3 ligase ligand, Ligand for PROTAC® research

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Size/SKUAvailabilityPrice
100 mg
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$348.00

About This Item

Empirical Formula (Hill Notation):
C13H13N3O3
CAS Number:
Molecular Weight:
259.26
UNSPSC Code:
12352101
NACRES:
NA.22
MDL number:

$348.00


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ligand

C5 Lenalidomide

Quality Segment

assay

≥95%

form

powder

reaction suitability

reagent type: ligand

technique(s)

targeted protein degradation: suitable

storage temp.

2-8°C

SMILES string

NC1=CC=C2C(CN(C3CCC(NC3=O)=O)C2=O)=C1

InChI

1S/C13H13N3O3/c14-8-1-2-9-7(5-8)6-16(13(9)19)10-3-4-11(17)15-12(10)18/h1-2,5,10H,3-4,6,14H2,(H,15,17,18)

InChI key

WLUIQUZGNPAKRL-UHFFFAOYSA-N

Application

C5 Lenalidomide is a derivative of the Cereblon (CRBN)-binding ligand lenalidomide, which possesses an amine at the C4 position. C5 Lenalidomide can be used to bind the CRBN E3 ubiquitin ligase in targeted protein degradation research or in the synthesis of protein degraders with a C5 exit vector. Learn more about proteolysis-targeting chimeras (PROTACs) and the building blocks to design them in our Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

Legal Information

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

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This Item
920754911739920797
description

≥95%

description

-

description

≥95%

description

≥95%

form

powder

form

solid

form

powder

form

powder or crystals

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

assay

≥95%

assay

-

assay

≥95%

assay

≥95%

reaction suitability

reagent type: ligand

reaction suitability

reagent type: ligand-linker conjugate, reactivity: carboxyl reactive

reaction suitability

reagent type: ligand-linker conjugate, reactivity: carboxyl reactive

reaction suitability

reactivity: carboxyl reactive, reagent type: ligand-linker conjugate

ligand

C5 Lenalidomide

ligand

C5 Lenalidomide

ligand

C5 Lenalidomide

ligand

C5 Lenalidomide


Pictograms

Health hazard

Signal Word

Warning

Hazard Codes

Hazard Classifications

Repr. 2 - STOT RE 2

Target Organs

Blood

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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