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Conjugated Polymer Nanoparticles incorporating iron oxide

fluorescence λem 435 nm, 100 μg/mL in H2O

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Synonym(s):
Conjugated polymer nanoparticles, Fluorescent magnetic nanoparticles, Fluorescent nanoparticles, Magneto-conjugated polymer nanoparticles

form

nanoparticles

Quality Level

concentration

100 μg/mL in H2O

fluorescence

λem 435 nm

storage temp.

2-8°C

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Application

Iron oxide containing conjugated polymer nanoparticles are water-soluble nanoparticles compromising of light-emitting polymer and iron oxide. The presence of iron oxide in core makes these fluorescent nanoparticles distinctly different than conventional dyes as it allows their manipulation with a magnetic field. These nanoparticles possess a ′core-shell′ structure where light-emitting polymer and iron oxide are encapsulated in biocompatible surfactant.
The ′core-shell′ structure consisting of polymer and iron oxide in the core and the biocompatible surfactant in the surrounding shell allows easy covalently bonding of these nanoparticles with biomolecules such streptavidin, antibodies, proteins, nucleic acids, etc and make them suitable for the following applications:
  • Fluorescence Microscopy (high content screening, live cell tracking and 3-D cell imaging)
  • Immunohistochemistry and Immunocytochemistry
  • Flow Cytometry
  • Rapid Diagnostic Tests (RDTs)
  • Tissue Imaging
  • 2-Photon Imaging
  • NIR Imaging

Storage and Stability

The robustness of CPNs enables them to be used under high intensity illumination and in extreme experimental conditions if required, while their 24-month shelf-life permits convenient storage at ambient temperatures.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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General synthesis of high-performing magneto-conjugated polymer core?shell nanoparticles for multifunctional theranostics.
Yan H, et al.
Nano Research, 10, 704-704 (2017)
Philip Howes et al.
Journal of the American Chemical Society, 132(28), 9833-9842 (2010-06-25)
Hybrid nanoparticles which incorporate multiple functionalities, such as fluorescence and magnetism, can exhibit enhanced efficiency and versatility by performing several tasks in parallel. In this study, magnetic-fluorescent semiconductor polymer nanospheres (MF-SPNs) have been synthesized by encapsulation of hydrophobic conjugated polymers

Articles

As a result of their properties, CPNs can deliver enhanced sensitivity, improved stability, and rapid, reliable results across various life science assays, including lateral flow and western blot. This innovative technology may provide benefits in the lab and allow the development of portable, point-of-care rapid diagnostic tests to help meet current and future healthcare needs.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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