Yes, any of GelMA based bioinks, such as 918741, can be used for DLP 3D printing, but some adjustments are needed. The DLP printer should have a heating function, or the bioink needs to be heated before printing to make the GelMA a low viscosity liquid. Additionally, a photo-absorber needs to be added to the bioink to scavenge scattered light.
918741
TissueFab® bioink
(Gel)ma -VIS/405nm, low endotoxin
Synonym(s):
Bioink, GelMA, Gelatin methacrylamide, Gelatin methacrylate, Gelatin methacryloyl
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10 ML
$494.00
About This Item
UNSPSC Code:
12352201
NACRES:
NA.23
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Quality Level
description
suitable for 3D bioprinting applications
with LAP photoinitiator
sterility
sterile-filtered
form
viscous liquid
impurities
≤5 CFU/g Bioburden (Fungal)
≤5 CFU/g Bioburden (Total Aerobic)
<50 EU/mL Endotoxin
color
colorless to pale yellow
particle size
0.2 μm
pH
6.5-7.5
application(s)
3D bioprinting
storage temp.
2-8°C
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Application
TissueFab® GelMA-Vis-LAP bioink is a gelatin methacryloyl (GelMA) based bioink for 3D bioprinting applications. LAP is used as the photoinitiator, which allows blue light photocrosslinking of the printed structure. The formulation is optimized for high printing fidelity and cell viability. The low endotoxin level of this product is lower than 50 EU/mL.
Gelatin methacryloyl (GelMA) is a polymerizable hydrogel material derived from natural extracellular matrix (ECM) components. Due to its low cost, abundance, and retention of natural cell binding motifs, gelatin has become a highly sought material for tissue engineering applications. The addition of photocrosslinkable methacrylamide functional groups in GelMA allows the synthesis of biocompatible, biodegradable, and non-immunogenic hydrogels that are stable in biologically relevant conditions and promote cell adhesion, spreading, and proliferation.
Gelatin methacryloyl (GelMA) is a polymerizable hydrogel material derived from natural extracellular matrix (ECM) components. Due to its low cost, abundance, and retention of natural cell binding motifs, gelatin has become a highly sought material for tissue engineering applications. The addition of photocrosslinkable methacrylamide functional groups in GelMA allows the synthesis of biocompatible, biodegradable, and non-immunogenic hydrogels that are stable in biologically relevant conditions and promote cell adhesion, spreading, and proliferation.
Legal Information
TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
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Y Shi et al.
Biomedical materials (Bristol, England), 13(3), 035008-035008 (2018-01-09)
Three-dimensional bioprinting is an emerging technology for fabricating living 3D constructs, and it has shown great promise in tissue engineering. Bioinks are scaffold materials mixed with cells used by 3D bioprinting to form a required cell-laden structure. In this paper
Wanjun Liu et al.
Advanced healthcare materials, 6(12) (2017-05-04)
Bioprinting is an emerging technique for the fabrication of 3D cell-laden constructs. However, the progress for generating a 3D complex physiological microenvironment has been hampered by a lack of advanced cell-responsive bioinks that enable bioprinting with high structural fidelity, particularly
B Duan et al.
Acta biomaterialia, 10(5), 1836-1846 (2013-12-18)
Tissue engineering has great potential to provide a functional de novo living valve replacement, capable of integration with host tissue and growth. Among various valve conduit fabrication techniques, three-dimensional (3-D) bioprinting enables deposition of cells and hydrogels into 3-D constructs
Weitao Jia et al.
Biomaterials, 106, 58-68 (2016-08-24)
Despite the significant technological advancement in tissue engineering, challenges still exist towards the development of complex and fully functional tissue constructs that mimic their natural counterparts. To address these challenges, bioprinting has emerged as an enabling technology to create highly
Wanjun Liu et al.
Biofabrication, 10(2), 024102-024102 (2017-11-28)
Bioinks with shear-thinning/rapid solidification properties and strong mechanics are usually needed for the bioprinting of three-dimensional (3D) cell-laden constructs. As such, it remains challenging to generate soft constructs from bioinks at low concentrations that are favorable for cellular activities. Herein
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Bioinks enable 3D bioprinting of tissue constructs for drug screening and transplantation; select suitable bioinks for specific tissue engineering.
Learn how 3D bioprinting is revolutionizing drug discovery with highly-controllable cell co-culture, printable biomaterials, and its potential to simulate tissues and organs. This review paper also compares 3D bioprinting to other advanced biomimetic techniques such as organoids and organ chips.
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Are there any GelMA products suitable for DLP 3D printing, particularly those that are part of the TissueFab line?
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