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MilliporeSigma

919373

Low endotoxin alginate

Medium viscosity

Synonym(s):

Alginic acid, Sodium alginate

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About This Item

NACRES:
NA.23
UNSPSC Code:
12352201

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Product Name

Low endotoxin alginate, Medium viscosity

form

lyophilized powder

impurities

<10 CFU/g Bioburden
<100 EU/g Endotoxin

color

white to pale yellow

storage temp.

2-8°C

Quality Level

100

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This Item
918652920819913057
Sigma-Aldrich

Sigma-Aldrich

919373

Low endotoxin alginate

Low endotoxin alginate solution Medium viscosity, 0.2&#160;&#956;m, sterile-filtered

Sigma-Aldrich

918652

Low endotoxin alginate solution

mPEG functionalized alginate 5% +/- 2% PEGylation, PEG average Mn 1k

Sigma-Aldrich

920819

mPEG functionalized alginate

Alginate methacrylate medium viscosity, average degree of methacrylation 25%

Sigma-Aldrich

913057

Alginate methacrylate

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

form

lyophilized powder

form

viscous liquid

form

(solid or chunk(s) or fiber)

form

(Powder or chunk(s) or fibers)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

color

white to pale yellow

color

colorless to pale yellow

color

white to off-white

color

light yellow

impurities

<10 CFU/g Bioburden

impurities

<10 EU/g Endotoxin, <5 CFU/g Bioburden (Fungal), <5 CFU/g Bioburden (Total Aerobic)

impurities

-

impurities

-

Application

This product is low endotoxin version alginate, it is lyophilized powder and ready to be used in biomedical applications.

Alginate is an anionic polysaccharide that is widely used in pharmaceutical and biomedical applications due to its non-animal origin, low toxicity, biocompatibility, and biodegradability. Alginate hydrogels are commonly used to fabricate tissue engineering scaffolds, bioinks for 3D bioprinting, and nanocarriers for drug & gene delivery. Alginate is commonly crosslinked into a hydrogel via ionic-crosslinking with divalent cations (e.g., Ca2+).

Packaging

500mg in glass bottle

Storage Class

13 - Non Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCT2848
MKCP4846

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Jia Jia et al.
Acta biomaterialia, 10(10), 4323-4331 (2014-07-08)
Recent advances in three-dimensional (3-D) printing offer an excellent opportunity to address critical challenges faced by current tissue engineering approaches. Alginate hydrogels have been used extensively as bioinks for 3-D bioprinting. However, most previous research has focused on native alginates
Kuen Yong Lee et al.
Progress in polymer science, 37(1), 106-126 (2011-11-30)
Alginate is a biomaterial that has found numerous applications in biomedical science and engineering due to its favorable properties, including biocompatibility and ease of gelation. Alginate hydrogels have been particularly attractive in wound healing, drug delivery, and tissue engineering applications
Tarun Agarwal et al.
ACS applied materials & interfaces, 8(47), 32132-32145 (2016-12-10)
Success of bone tissue engineering (BTE) relies on the osteogenic microarchitecture of the biopolymeric scaffold and appropriate spatiotemporal distribution of therapeutic molecules (growth factors and drugs) inside it. However, the existing technologies have failed to address both the issues together.
Eneko Axpe et al.
International journal of molecular sciences, 17(12) (2016-11-30)
Three-dimensional (3D) bioprinting is on the cusp of permitting the direct fabrication of artificial living tissue. Multicellular building blocks (bioinks) are dispensed layer by layer and scaled for the target construct. However, only a few materials are able to fulfill

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