93094

Triphenylphosphine, polymer-bound

100-200 mesh, extent of labeling: ~1-1.5 mmol/g Capacity (Phosphor)

• Synonym(s): Copolymer of styrene and divinylbenzene, diphenylphosphinated, Diphenylphosphino-polystyrene, Polystyrene crosslinked with divinylbenzene, diphenylphosphinated
• Linear Formula: -C₆H₄P(C₆H₅)₂
• CAS Number: 39319-11-4
• Molecular Weight: 262.29
• MDL number: MFCD00148025
• UNSPSC Code: 12352128
• PubChem Substance ID: 57653516
• NACRES: NA.22

Properties

• form: solid
• reaction suitability: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reaction type: solution phase peptide synthesis; reagent type: ligand
• extent of labeling: ~1-1.5 mmol/g Capacity (Phosphor)
• matrix: crosslinked with 1% DVB
• particle size: 100-200 mesh
• functional group: phosphine
• storage temp.: 2-8°C
• SMILES string: c1ccc(cc1)P(c2ccccc2)c3ccccc3
• InChI: 1S/C18H15P/c1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15H
• InChI key: RIOQSEWOXXDEQQ-UHFFFAOYSA-N

Description

General description

Triphenylphosphine, polymer-bound is polystyrene crosslinked with divinylbenzene, widely used in many organic syntheses such as peptide synthesis, heterocycle synthesis, esterification, and total synthesis. It can be easily removed from the reaction products by simple filtration.[1]

Application

Triphenylphosphine, polymer-bound is used as a polymer support to synthesize dipeptides, olefins, aryl-alkyl ethers, and in the esterification of alkylphosphonic acids. It acts as a Lewis acid, and dehydrating agent when complexed with halogen, hence useful in the acetonation of sugars.[2] [3] [4] [5]

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves