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MilliporeSigma

934097

Sigma-Aldrich

Ovine collagen

methacrylate functionalized, low endotoxin

Synonym(s):

CollOvine™ MA

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About This Item

CAS Number:
9007-34-5
MDL number:
MFCD18251627
NACRES:
NA.28

Key Documents

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Quality Level

100

form

powder

impurities

Bioburden, none detected
≤0.1 EU/mg Endotoxin

color

white to off-white

functional group

methacrylate

storage temp.

2-8°C

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1 of 4

This Item
934119934100934070
Sigma-Aldrich

Sigma-Aldrich

934097

Ovine collagen

Ovine collagen SPDP functionalized, low endotoxin

Sigma-Aldrich

934119

Ovine collagen

Ovine collagen maleimide functionalized, low endotoxin

Sigma-Aldrich

934100

Ovine collagen

Sigma-Aldrich

Sigma-Aldrich

934070

Ovine collagen

form

powder

form

lyophilized

form

lyophilized powder

form

liquid

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

-

impurities

Bioburden, none detected

impurities

Bioburden, none detected, ≤0.1 EU/mg Endotoxin

impurities

Bioburden, none detected, low endotoxin, ≤0.1 EU/mg Endotoxin

impurities

low endotoxin, ≤100 EU/g Endotoxin (collagen)

color

white to off-white

color

white to off-white

color

white to off-white

color

-

functional group

methacrylate

functional group

SPDP

functional group

maleimide

functional group

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

General description

Collagen is a major component of the extracellular matrix (ECM) and offers low immunogenicity, a porous structure, good permeability, and biocompatibility to promote cell viability, adhesion, spreading, proliferation and differentiation.

Methacrylate functionalized collagen is a polymerizable hydrogel material derived from low endotoxin ovine collagen. The addition of photocrosslinkable methacrylate functional groups allows the photopolymerization of biocompatible, biodegradable, and non-immunogenic hydrogels which can encapsulate cells and be used in many biomedical applications. This methacrylate functionalized collagen is also a great alternative to other naturally derived collagens such as those derived from bovine or porcine.

Application

  • 3D bioprinting
  • Tissue engineering
  • Drug delivery
  • Regenerative medicine
  • Cell culture, encapsulation, expansion and differentiation

Features and Benefits

  • Certified Disease Free Sheep
  • 93-97% Type I Collagen
  • 3-7% Type III Collagen
  • 99% Purity
  • Prion Free

Legal Information

CollOvine is a trademark of OviGenex LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Collagen as Bioink for Bioprinting: A Comprehensive Review
Osidak E O, et al.
International Journal of Bioprinting, 6, 270-270 (2020)
Elizabeth E Antoine et al.
Tissue engineering. Part B, Reviews, 20(6), 683-696 (2014-06-14)
Type I collagen hydrogels have been used successfully as three-dimensional substrates for cell culture and have shown promise as scaffolds for engineered tissues and tumors. A critical step in the development of collagen hydrogels as viable tissue mimics is quantitative
Atiqah Salleh et al.
Biomedicines, 10(4), 816-816 (2022-04-24)
Tissue engineering products have grown rapidly as an alternative solution available for chronic wound and burn treatment. However, some drawbacks include additional procedures and a lack of antibacterial properties that can impair wound healing, which are issues that need to
Jana Stepanovska et al.
Biomedicines, 9(9), 1137-1137 (2021-09-29)
Bioprinting is a modern tool suitable for creating cell scaffolds and tissue or organ carriers from polymers that mimic tissue properties and create a natural environment for cell development. A wide range of polymers, both natural and synthetic, are used

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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