946028

Methacrylamide tert-butyl carbazate

• Synonym(s): 1,1-Dimethylethyl 2-(2-methyl-1-oxo-2-propen-1-yl)hydrazinecarboxylate (ACI), Hydrazinecarboxylic acid, 2-(2-methyl-1-oxo-2-propenyl)-, 1,1-dimethylethyl ester (9CI)

Properties

• InChI: 1S/C9H16N2O3/c1-6(2)7(12)10-11-8(13)14-9(3,4)5/h1H2,2-5H3,(H,10,12)(H,11,13)
• SMILES string: O=C(N(C(C)(C)C)NC(C(C)=C)=O)O
• assay: ≥95%
• form: solid
• mol wt: 200.24
• storage temp.: 2-8°C
• Quality Level: 100

Description

General description

Methacrylamide tert-butyl carbazate is a versatile monomer that combines a methacrylamide unit with a tert-butyl carbazate group. The methacrylamide part allows easy polymerization, while the carbazate group offers reactive sites for further chemical modifications or linking to biomolecules. The bulky tert-butyl group helps protect the structure and improves stability during handling. This combination makes it useful for creating advanced polymers, crosslinking agents, and materials for biomedical applications. Our Methacrylamide tert-butyl carbazate comes with of Purity: ≥ 95% and with a stable formulation for research applications in synthetic chemistry and materials science for the development of polymers and other functional materials. The product is soluble in Chloroform and CH₂Cl₂.

Application

Methacrylamide tert-butyl carbazate is designed for various applications in research, particularly in the fields of organic synthesis and medicinal chemistry. One of the notable applications of this compound is in palladium-catalyzed cross-coupling reactions. Additionally, solid-phase peptide synthesis is another critical area where this compound is utilized. It facilitates the assembly of peptides. [1][2] Methacrylamide derivatives (including tert-butyl substituted methacrylamides) are used to synthesize temperature- and pH-responsive polyampholytes for drug delivery and tissue engineering scaffolds.[3]

Features and Benefits

• Higher guaranteed purity reduces purification steps and improves reaction efficiency
• Built-in vinyl C=C allows direct copolymerization for faster network formation
• tert-Butyl Carbazate (Boc-protected hydrazide) provides stability and allows selective, mild deprotection, streamlining synthesis.