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C011

Sigma-Aldrich

cis-2-Methyl-5-trimethylammoniummethyl-1,3-oxathiolane iodide

Synonym(s):
OXA-22
Empirical Formula (Hill Notation):
C8H18INOS
CAS Number:
Molecular Weight:
303.20
MDL number:
PubChem Substance ID:
NACRES:
NA.22

color

yellow

Quality Level

solubility

H2O: soluble
methanol: soluble

SMILES string

[I-].C[C@H]1O[C@H](CS1)C[N+](C)(C)C

InChI

1S/C8H18NOS.HI/c1-7-10-8(6-11-7)5-9(2,3)4;/h7-8H,5-6H2,1-4H3;1H/q+1;/p-1/t7-,8-;/m0./s1

InChI key

TWNAKQKXXMGYQT-WSZWBAFRSA-M

Packaging

5 mg in glass bottle

Biochem/physiol Actions

Potent muscarinic acetylcholine receptor agonist.

Caution

Photosensitive

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

More Documents

Quotes and Ordering

R M Eglen et al.
Naunyn-Schmiedeberg's archives of pharmacology, 342(4), 394-399 (1990-10-01)
1. para-Fluoro-hexahydrosila-difenidol (p-F-HHSiD) has been proposed as an M3 selective antagonist. However, the M3 selectivity is variable in that it exhibits a high pA2 value for M3 muscarinic receptors in guinea-pig ileum but a low value at muscarinic receptors in
P Angeli et al.
British journal of pharmacology, 85(4), 783-786 (1985-08-01)
The efficacy and affinity of nine pentatomic cyclic muscarinic agonists were determined on the guinea-pig ileum, according to the method of Furchgott & Bursztyn (1967). The efficacy and affinity of these agonists are affected differently by structural modifications. Our results
Zizhuo Su et al.
American journal of translational research, 12(7), 3964-3973 (2020-08-11)
Cyclophilin A (CyPA) plays an important role in the progression of atherosclerosis. Additionally, it has been reported that lysosomal function is markedly impaired in atherosclerosis induced by oxidized low-density lipoprotein (ox-LDL). As the CyPA degradation pathway remains to be elucidated

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