D196800

Sigma-Aldrich

1-Fluoro-2,4-dinitrobenzene

99%

Synonym(s):
Sanger reagent, DNFB, DNPF, FDNB, 2,4-Dinitro-1-fluorobenzene
Linear Formula:
(O2N)2C6H3F
CAS Number:
Molecular Weight:
186.10
Beilstein/REAXYS Number:
398632
EC Number:
MDL number:

assay

99%

refractive index

n20/D 1.569 (lit.)

bp

178 °C/25 mmHg (lit.)

mp

25-27 °C (lit.)

density

1.482 g/mL at 25 °C (lit.)

SMILES string

[O-][N+](=O)c1ccc(F)c(c1)[N+]([O-])=O

InChI

1S/C6H3FN2O4/c7-5-2-1-4(8(10)11)3-6(5)9(12)13/h1-3H

InChI key

LOTKRQAVGJMPNV-UHFFFAOYSA-N

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Application

Reagent for labeling terminal amino acid groups. Used in the detection of phenols. Suppresses the action potential in nerves. Induces contact hypersensitivity.

Certificate of Analysis

Certificate of Origin

Journal of Chromatography A, 44, 251-251 (1969)
Suppression of the action potential in nerve by nitrobenzene derivatives.
I M Cooke et al.
Proceedings of the National Academy of Sciences of the United States of America, 60(2), 470-477 (1968-06-01)
W R Welches et al.
Biochemistry, 20(3), 512-517 (1981-02-03)
Bacterial luciferase catalyzes the mixed-function oxidation of a long-chain saturated aldehyde and FMNH2 to yield the carboxylic acid, FMN, and blue-green light. The enzyme was inactivated by 2,4-dinitrofluorobenzene (FDNB) with an observed second-order rate constant (k2(obsd) of 157 M-1 min-1...
The terminal peptides of insulin.
F SANGER
The Biochemical journal, 45(5), 563-574 (1949-01-01)

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