D8402

Sigma-Aldrich

1,2-Diacetylhydrazine

98%

Linear Formula:
CH3CONHNHCOCH3
CAS Number:
Molecular Weight:
116.12
EC Number:
MDL number:
PubChem Substance ID:

Quality Level

assay

98%

bp

209 °C/15 mmHg (lit.)

mp

138-140 °C (lit.)

SMILES string

CC(=O)NNC(C)=O

InChI

1S/C4H8N2O2/c1-3(7)5-6-4(2)8/h1-2H3,(H,5,7)(H,6,8)

InChI key

ZLHNYIHIHQEHJQ-UHFFFAOYSA-N

Related Categories

Packaging

25 g in glass bottle

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. D8402.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Pictograms

Exclamation mark

Signal Word

Warning

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

E B Bhalerao et al.
Indian journal of physiology and pharmacology, 29(2), 83-88 (1985-04-01)
Patients suffering from pulmonary tuberculosis were investigated for the levels of isoniazid (INH) and its metabolites viz. acetyl-INH, mono and diacetyl hydrazines and ammonia. It was observed that 50% of the patients are slow inactivators of INH and almost all...
W von Sassen et al.
Journal of chromatography, 338(1), 113-122 (1985-02-27)
A high-performance liquid chromatographic assay for the determination of isoniazid, acetylisoniazid, acetylhydrazine and diacetylhydrazine (plasma and urine) was developed. The m-chlorobenzoyl derivatives of isoniazid, acetylhydrazine and the internal standard propionylhydrazine were prepared, separated on a RP-18 column and detected at...
Ramachandran Azhakar et al.
Dalton transactions (Cambridge, England : 2003), 41(5), 1529-1533 (2011-12-14)
The reaction of N-heterocyclic silylene (NHSi) L [L = CH{(C[double bond, length as m-dash]CH(2))(CMe)(2,6-iPr(2)C(6)H(3)N)(2)}Si] with benzoylhydrazine, 1,2-dicarbethoxyhydrazine, 1,2-diacetylhydrazine and 1,2-bis(tert-butoxycarbonyl)hydrazine in 1 : 1 molar ratio resulted in compounds 1-4 with an almost quantitative yield and five coordinate silicon atoms....
Qiqi Zhao et al.
Journal of agricultural and food chemistry, 56(13), 5254-5259 (2008-06-11)
A series of novel N-substituted phenoxysulfenyl- N'- tert-butyl- N, N'-diacylhydrazines were designed and synthesized as insect growth regulators via the key intermediates N-chlorosulfenyl- N'- tert-butyl- N, N'-diacylhydrazines. Compared to the parent compounds, these N-substituted phenoxysulfenyl derivatives displayed better solubility and...
J A Timbrell et al.
Human toxicology, 3(6), 485-495 (1984-12-01)
The urinary metabolite profile of isoniazid has been studied in patients receiving the drug as therapy for tuberculosis and the profile in patients suffering liver damage due to isoniazid compared with that in control patients. There were no consistent differences...

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