M75802

Sigma-Aldrich

3-Methylpyrazole

97%

Empirical Formula (Hill Notation):
C4H6N2
CAS Number:
Molecular Weight:
82.10
Beilstein/REAXYS Number:
1454
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

assay

97%

refractive index

n20/D 1.495 (lit.)

bp

204 °C (lit.)

density

1.02 g/mL at 25 °C (lit.)

SMILES string

Cc1cc[nH]n1

InChI

1S/C4H6N2/c1-4-2-3-5-6-4/h2-3H,1H3,(H,5,6)

InChI key

XKVUYEYANWFIJX-UHFFFAOYSA-N

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Signal Word

Danger

Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN 3265 8 / PGII

WGK Germany

WGK 3

Flash Point(F)

218.3 °F - closed cup

Flash Point(C)

103.5 °C - closed cup

B Schulz et al.
Die Pharmazie, 43(1), 29-31 (1988-01-01)
The release behaviour of the antimicrobially active 3(5)-methylpyrazole from matrix systems prepared from maleic anhydride copolymers as well as from copolymers of maleic esters and maleic amides was studied. Under alkaline conditions erosion is the predominant release mechanism compared to...
B Schulz et al.
Die Pharmazie, 40(8), 548-552 (1985-08-01)
The release of 3-methylpyrazole from monolithic polymer films into aqueous media has been studied. The diffusion of the active agent decreased with increasing of the content of acetate groups in reacetylated poly(vinyl alcohols) and with increasing of the ester lengths...
B Schulz et al.
Die Pharmazie, 41(2), 118-120 (1986-02-01)
The diffusion of 3-methylpyrazole through a synthetic polymer matrix and the effect of the solubility of the bioactive agent in polymers on the release behaviour of polymer combinations were studied. With increasing hydrophilicity of the polymer both the diffusion and...
J Hauser et al.
The Journal of pharmacology and experimental therapeutics, 256(2), 592-598 (1991-02-01)
We tested the hypothesis that the gastrotoxicity of ethanol and other damaging agents is influenced through the modulation of alcohol dehydrogenase (ADH) by using either the ADH-inhibitor pyrazole or the noninhibitor derivatives of pyrazole. In time course experiments, the protection...
E S Fiala et al.
Journal of cancer research and clinical oncology, 113(2), 145-150 (1987-01-01)
Using a hybrid ion-exchange reverse phase HPLC system, we found that F344 rat liver microsomes, in the presence of an NADPH-generating system, can metabolize methylazoxymethanol (MAM), a colon and liver carcinogen, to methanol and formic acid. This is in contrast...

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