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1-Methyl-4-imidazoleacetic acid hydrochloride

Empirical Formula (Hill Notation):
C6H8N2O2 · HCl
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J H Butterfield
The British journal of dermatology, 138(3), 489-495 (1998-05-15)
Six patients with documented systemic mast cell disease were enrolled in a 1-year, phase I study to determine the possible benefits of interferon alpha-2b (IFN-alpha). IFN-alpha therapy was begun at a dosage of 0.5 million units/day (MU/day) by subcutaneous injection
G Granerus et al.
The British journal of dermatology, 139(5), 858-861 (1999-01-20)
Serum tryptase was measured with the B12 and G5 antibody-based immunoassays in 25 adult patients with mastocytosis and in 18 controls. Twelve patients had uncomplicated cutaneous mastocytosis (urticaria pigmentosa) and 13 had urticaria pigmentosa with systemic symptoms. Tryptase levels were
S A Kemink et al.
Nederlands tijdschrift voor geneeskunde, 140(24), 1277-1279 (1996-06-15)
Out of 21 male patients with osteoporosis who visited an outpatient clinic for endocrine diseases in two years (1994-1995), three had systemic mastocytosis as diagnosed histopathologically. Two of these had characteristic features of urticaria pigmentosa, consisting of multiple brown nodules
Philippe Casassus et al.
British journal of haematology, 119(4), 1090-1097 (2002-12-11)
Systemic mastocytosis (SM) is characterized by proliferation of mast cells in various organs, which may release a wide variety of mediators, thereby explaining the broad clinical spectrum of disease manifestations. The potentially life-threatening systemic symptoms and tumoral proliferation are poorly
K Hartmann et al.
The journal of investigative dermatology. Symposium proceedings, 6(2), 143-147 (2002-01-05)
Mastcytosis is a rare disease characterized by an abnormal increase of mast cells in tissues. The skin is the organ most frequently involved, but mast cells also accumulate in the bone marrow, gastrointestinal tract, lymph nodes, spleen, and liver. Recent

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