All Photos(1)

T1388

Sigma-Aldrich

2-Thiophenecarboxylic acid hydrazide

≥98%

Empirical Formula (Hill Notation):
C5H6N2OS
CAS Number:
Molecular Weight:
142.18
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

≥98%

mp

136-139 °C (lit.)

SMILES string

NNC(=O)c1cccs1

InChI

1S/C5H6N2OS/c6-7-5(8)4-2-1-3-9-4/h1-3H,6H2,(H,7,8)

InChI key

SOGBOGBTIKMGFS-UHFFFAOYSA-N

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Harindra D Sathkumara et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(34), 20848-20859 (2020-08-12)
Tuberculosis (TB) claims 1.5 million lives per year. This situation is largely due to the low efficacy of the only licensed TB vaccine, Bacillus Calmette-Guérin (BCG) against pulmonary TB. The metabolic disease type 2 diabetes (T2D) is a risk factor...
R Prabhakar et al.
Tubercle, 68(1), 3-17 (1987-03-01)
This study, conducted in Madras, India and in Madison, Wisconsin, USA, was concerned with the virulence of isolates of Mycobacterium tuberculosis obtained from the sputum of individuals living in the Chingleput district of south India. The following results were obtained....
I Bouzouita et al.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 22(6), 661-666 (2018-06-05)
Phenotypic tests used to detect pyrazinamide (PZA) resistance are slow and have a high rate of false resistance. To evaluate the accuracy of pncA sequencing for the detection of PZA resistance in Mycobacterium tuberculosis strains isolated in Tunisia. A total...
M D Yates et al.
Tubercle, 63(1), 55-61 (1982-03-01)
Strains of Mycobacterium tuberculosis were divided into 'classical' and 'Asian' types according to their susceptibility to thiophen-2-carboxylic acid hydrazide (TCH). A study of 6638 new cases of tuberculosis showed that there was a much higher incidence of non-pulmonary disease among...
M D Yates et al.
Tubercle, 65(4), 295-299 (1984-12-01)
Thiophen-2-carboxylic acid hydrazide (TCH) is used to distinguish TCH-sensitive bovine, 'Asian human' and 'African' strains from TCH-resistant 'classical' human strains of Mycobacterium tuberculosis. It has been claimed that this test cannot be applied to isoniazid-resistant strains as these also become...

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