W296902

Sigma-Aldrich

Pyruvaldehyde solution

40 wt. % in H2O

Synonym(s):
Pyruvaldehyde, Acetylformaldehyde, Pyruvic aldehyde, Methylglyoxal solution
Linear Formula:
CH3COCHO
CAS Number:
Molecular Weight:
72.06
FEMA Number:
2969
Beilstein/REAXYS Number:
906750
Council of Europe no.:
105
MDL number:
PubChem Substance ID:
Flavis number:
7.001
NACRES:
NA.21

Quality Level

biological source

synthetic

grade

Halal

concentration

40 wt. % in H2O

refractive index

n20/D 1.41

density

1.178 g/mL at 25 °C

Documentation

see Safety & Documentation for available documents

Featured Industry

Flavors and Fragrances

Organoleptic

caramel

food allergen

no known allergens

storage temp.

2-8°C

SMILES string

[H]C(=O)C(C)=O

InChI

1S/C3H4O2/c1-3(5)2-4/h2H,1H3

InChI key

AIJULSRZWUXGPQ-UHFFFAOYSA-N

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General description

Pyruvaldehyde solution may be used along with ammonium salts to prepare aqueous solutions that mimic atmospheric aerosol compositions to study the formation of absorbing secondary organic materials.

Packaging

100 g in glass bottle
1 kg in glass bottle
10 kg in poly drum

Other Notes

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Signal Word

Warning

Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN 3265 8 / PGIII

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Secondary organic material formed by methylglyoxal in aqueous aerosol mimics.
Sareen N, et al.
Atmospheric Chemistry and Physics, 10(3) (2010)
Björn Kuhla et al.
Annals of the New York Academy of Sciences, 1043, 211-216 (2005-07-23)
The accumulation of advanced glycation end products (AGEs) in brains with Alzheimer's disease (AD) has been implicated in the formation of insoluble deposits such as amyloid plaques and neurofibrillary tangles. AGEs are also known to activate glia, resulting in inflammation...
Weijing Cai et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(13), 4940-4945 (2014-02-26)
Age-associated dementia and Alzheimer's disease (AD) are currently epidemic. Neither their cause nor connection to the metabolic syndrome (MS) is clear. Suppression of deacetylase survival factor sirtuin 1 (SIRT1), a key host defense, is a central feature of AD. Age-related...
Xiao-Yan Zou et al.
The Journal of investigative dermatology, 135(2), 589-598 (2014-09-04)
Glyoxalase I (GLO1) is a methylglyoxal detoxification enzyme being implicated in the progression of multiple malignancies. However, currently, the role of GLO1 in human nonmelanoma skin tumors remains unclear. To explore the expression of GLO1 in cutaneous neoplasms and its...
Georg T Wondrak et al.
Biochemical pharmacology, 63(3), 361-373 (2002-02-21)
Tissue deterioration and aging have long been associated with the accumulation of chemically induced protein and DNA damage. Reactive oxygen species (ROS) and reactive carbonyl species (RCS), especially alpha-dicarbonyl compounds, are key mediators of damage caused by oxidative stress, glycation...

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