W358509

Sigma-Aldrich

L-Phenylalanine

99%, FCC

Synonym(s):
(S)-2-Amino-3-phenylpropionic acid
Linear Formula:
C6H5CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
165.19
FEMA Number:
3585
Beilstein/REAXYS Number:
1910408
EC Number:
Council of Europe no.:
10488
MDL number:
PubChem Substance ID:
Flavis number:
17.018
NACRES:
NA.21

Quality Level

biological source

synthetic

grade

Kosher

reg. compliance

FCC
FDA 21 CFR 172.320

assay

99%

optical activity

[α]25/D -34.2°, c = 2 in H2O (dried basis)

mp

270-275 °C (dec.) (lit.)

solubility

H2O: soluble 16.5 g/L at 20 °C (completely)

Documentation

see Safety & Documentation for available documents

Featured Industry

Flavors and Fragrances

Organoleptic

odorless

food allergen

no known allergens

SMILES string

N[C@@H](Cc1ccccc1)C(O)=O

InChI

1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1

InChI key

COLNVLDHVKWLRT-QMMMGPOBSA-N

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Related Categories

Packaging

5 kg in fiber drum
1 kg in poly bottle

Other Notes

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Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Ann Mullally et al.
Blood, 121(18), 3692-3702 (2013-03-15)
Interferon-α (IFNα) is an effective treatment of patients with myeloproliferative neoplasms (MPNs). In addition to inducing hematological responses in most MPN patients, IFNα reduces the JAK2V617F allelic burden and can render the JAK2V617F mutant clone undetectable in some patients. The...
Vimesh A Avlani et al.
American journal of physiology. Endocrinology and metabolism, 304(10), E1097-E1104 (2013-03-28)
In addition to its acute effects on hormone secretion, epithelial transport, and shape change, the calcium-sensing receptor (CaSR) modulates the expression of genes that control cell survival, proliferation, and differentiation as well as the synthesis of peptide hormones and enzymes....
Stefanie Keil et al.
Pediatrics, 131(6), e1881-e1888 (2013-05-22)
Sapropterin dihydrochloride, the synthetic form of 6R-tetrahydrobiopterin (BH4), is an approved drug for the treatment of patients with BH4-responsive phenylketonuria (PKU). The purpose of this study was to assess genotypes and data on the long-term effects of BH4/sapropterin on metabolic...
John J Mitchell et al.
Genetics in medicine : official journal of the American College of Medical Genetics, 13(8), 697-707 (2011-05-11)
Phenylalanine hydroxylase deficiency is an autosomal recessive disorder that results in intolerance to the dietary intake of the essential amino acid phenylalanine. It occurs in approximately 1:15,000 individuals. Deficiency of this enzyme produces a spectrum of disorders including classic phenylketonuria...
Bart Pennings et al.
The American journal of clinical nutrition, 98(1), 121-128 (2013-05-03)
Older individuals generally experience a reduced food-chewing efficiency. As a consequence, food texture may represent an important factor that modulates dietary protein digestion and absorption kinetics and the subsequent postprandial protein balance. We assessed the effect of meat texture on...

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