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A7256

DL-Norepinephrine hydrochloride

crystalline, ≥97% (TLC)

Synonym(s):

(±)-1-(3,4-Dihydroxyphenyl)-2-aminoethanol hydrochloride, (±)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol hydrochloride, DL-Arterenol hydrochloride, DL-Noradrenaline hydrochloride

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1 G

$123.00

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$491.00

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About This Item

Linear Formula:
(HO)2C6H3CH(OH)CH2NH2 · HCl
CAS Number:
Molecular Weight:
205.64
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-229-8
Beilstein/REAXYS Number:
3707003
MDL number:
Assay:
≥97% (TLC)
Form:
crystalline

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SMILES string

NCC(C1=CC(O)=C(C=C1)O)O.Cl

InChI key

FQTFHMSZCSUVEU-UHFFFAOYSA-N

InChI

1S/C8H11NO3.ClH/c9-4-8(12)5-1-2-6(10)7(11)3-5;/h1-3,8,10-12H,4,9H2;1H

assay

≥97% (TLC)

form

crystalline

color

off-white to tan

solubility

water: soluble 50 mg/mL, clear to slightly hazy, faintly yellow to brownish-yellow

storage temp.

−20°C

Quality Level

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This Item
A7257H850243658
assay

≥97% (TLC)

assay

≥98%

assay

-

assay

-

solubility

water: soluble 50 mg/mL, clear to slightly hazy, faintly yellow to brownish-yellow

solubility

-

solubility

alcohol: 20 mg/mL, H2O: soluble

solubility

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

300

form

crystalline

form

crystalline

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

color

off-white to tan

color

off-white to tan

color

light tan

color

-

Application

DL-Norepinephrine hydrochloride is suitable adrenergic drug used in the following studies:
  • To investigate the effects of adrenergic drugs on lantern of larval fly.[1]
  • To evaluate the ability of α-adrenergic stimulation in the presence of elevated calcium levels to induce delayed after depolarizations and triggered activity in Purkinje fibers isolated from cat hearts.[2]
  • Simultaneous reduction and surface functionalization of graphene oxide by a one-step poly(norepinephrine) functionalization.[3]

General description

DL-Norepinephrine hydrochloride is an adrenergic drug.[1]

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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Simultaneous Reduction and Surface Functionalization of Graphene Oxide by Mussel-Inspired Chemistry.
Kang SM, et al.
Advances in Functional Materials, 21(1), 108-112 (2011)
Effect of adrenergic drugs on the lantern of the larval Photuris firefly.
A D Carlson
The Journal of experimental biology, 48(2), 381-387 (1968-04-01)
Yining Chen et al.
Journal of neurophysiology, 125(6), 2397-2407 (2021-05-13)
Sensory learning during critical periods in development has lasting effects on behavior. Neuromodulators like dopamine and norepinephrine (NE) have been implicated in various forms of sensory learning, but little is known about their contribution to sensory learning during critical periods.
S Kimura et al.
Circulation, 70(6), 1074-1082 (1984-12-01)
We studied the ability of alpha-adrenergic stimulation to induce delayed afterdepolarizations and triggered activity in Purkinje fibers from cat hearts in the presence of an elevated Ca++ concentration. Delayed afterdepolarizations could not be induced at drive cycle lengths of 200
Alexis N Orr et al.
International journal of molecular sciences, 22(5) (2021-04-04)
Transglutaminases (TGs) are crosslinking enzymes best known for their vascular remodeling in hypertension. They require calcium to form an isopeptide bond, connecting a glutamine to a protein bound lysine residue or a free amine donor such as norepinephrine (NE) or

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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