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A78403
4-Aminopyridine
98%
Synonym(s):
4-Pyridinamine, 4-Pyridylamine, 4AP, Fampridine
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$53.90
$153.00
$53.90
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InChI key
NUKYPUAOHBNCPY-UHFFFAOYSA-N
InChI
1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7)
SMILES string
Nc1ccncc1
assay
98%
form
crystals
bp
273 °C (lit.)
mp
155-158 °C (lit.)
solubility
H2O: 50 mg/mL, clear, colorless
Quality Level
Gene Information
human ... KCNA1(3736), KCNA10(3744), KCNA2(3737), KCNA3(3738), KCNA4(3739), KCNA5(3741), KCNA6(3742), KCNA7(3743), KCNB1(3745), KCNB2(9312), KCNC1(3746), KCNC2(3747), KCNC3(3748), KCNC4(3749), KCND1(3750), KCND2(3751), KCND3(3752), KCNF1(3754), KCNG1(3755), KCNG2(26251), KCNG3(170850), KCNG4(93107), KCNH1(3756), KCNH2(3757), KCNH3(23416), KCNH4(23415), KCNH5(27133), KCNH6(81033), KCNH7(90134), KCNH8(131096), KCNQ1(3784), KCNQ2(3785), KCNQ3(3786), KCNQ4(9132), KCNQ5(56479), KCNS1(3787), KCNS2(3788), KCNS3(3790), KCNV1(27012), KCNV2(169522)
mouse ... Kcna3(16491)
rat ... Grin2a(24409)
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This Item | |||
|---|---|---|---|
| assay 98% | assay ≥99% | assay 99% | assay 97% |
| solubility H2O: 50 mg/mL, clear, colorless | solubility DMF: soluble(lit.), DMSO: soluble(lit.), THF: soluble(lit.), acetone: soluble(lit.), acetonitrile: soluble(lit.), ethanol: soluble(lit.), isopropanol: soluble(lit.), methanol: soluble(lit.), water: soluble(lit.) | solubility - | solubility - |
| Quality Level 200 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| mp 155-158 °C (lit.) | mp 155-158 °C (lit.) | mp 54-58 °C (lit.) | mp 65-70 °C |
| form crystals | form solid | form crystals | form solid |
| bp 273 °C (lit.) | bp 273 °C (lit.) | bp 204-210 °C (lit.) | bp - |
General description
Application
- Catalyst in the regioselective acylation of N-tosylhydrazide.[3]
- Starting material in the synthesis of 4-aminopyridine derivatives for neurological disorder studies.[4]
- Precursor for the synthesis of enantiomerically pure 4-(pyrrolidino)pyridine (PPY) derivatives by cyclocondensation reaction.[5]
signalword
Danger
Hazard Classifications
Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
312.8 °F
flash_point_c
156 °C
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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