A79604

Sigma-Aldrich

4-Aminosalicylic acid

99%

Synonym(s):
4-Amino-2-hydroxybenzoic acid, PAS
Linear Formula:
H2NC6H3-2-(OH)CO2H
CAS Number:
Molecular Weight:
153.14
Beilstein/REAXYS Number:
473071
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

99%

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

application(s)

peptide synthesis: suitable

color

white to beige

mp

135-145 °C (lit.)

SMILES string

Nc1ccc(C(O)=O)c(O)c1

InChI

1S/C7H7NO3/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3,9H,8H2,(H,10,11)

InChI key

WUBBRNOQWQTFEX-UHFFFAOYSA-N

Gene Information

human ... PTPN1(5770)

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Application

4-Aminosalicylic acid (4-ASA) can be used in the synthesis of:
  • Azo derivatives of 4-ASA with anti-inflammatory effects.
  • Ammonium 4-aminosalicylate salt polymorphs which are used as pharmaceutical ingredients.
  • Salicylic acid-triazole analogs which are used as quorum sensing inhibitors against Pseudomonas aeruginosa.

Packaging

5, 100 g in glass bottle

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. A79604.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Design, Synthesis and Biological Evaluation of Triazole-Containing 2-Phenylindole and Salicylic Acid as Quorum Sensing Inhibitors Against Pseudomonas aeruginosa.
Srinivasarao S, et al.
ChemistrySelect, 3(32), 9170-9180 (2018)
Polymorphic ammonium salts of the antibiotic 4-aminosalicylic acid.
Andre V, et al.
Crystal Growth & Design, 12(6), 3082-3090 (2012)
Synthesis of azo derivatives of 4-aminosalicylic acid.
Zhao ZB, et al.
Chinese Chemical Letters = Zhongguo Hua Xue Kuai Bao, 18(6), 639-642 (2007)
Joan Cid et al.
Platelets, 26(2), 190-194 (2014-05-29)
Platelet refractoriness (PR) due to HLA alloimmunization is a common and serious complication of patients receiving long-term packed red blood cell and platelet transfusions. Although most alloimmunized patients will respond to HLA-matched platelets, 20-50% of patients will remain refractory even...
Maria João Forjaz et al.
Movement disorders : official journal of the Movement Disorder Society, 30(4), 545-551 (2014-12-30)
The Parkinson Anxiety Scale is a new scale developed to measure anxiety severity in Parkinson's disease specifically. It consists of three dimensions: persistent anxiety, episodic anxiety, and avoidance behavior. This study aimed to assess the measurement properties of the scale...

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