A8060

Sigma-Aldrich

Acrylic acid N-hydroxysuccinimide ester

≥90%

Synonym(s):
N-Acryloxysuccinimide
Empirical Formula (Hill Notation):
C7H7NO4
CAS Number:
Molecular Weight:
169.13
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

≥90%

application(s)

peptide synthesis: suitable

storage temp.

2-8°C

SMILES string

C=CC(=O)ON1C(=O)CCC1=O

InChI

1S/C7H7NO4/c1-2-7(11)12-8-5(9)3-4-6(8)10/h2H,1,3-4H2

InChI key

YXMISKNUHHOXFT-UHFFFAOYSA-N

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Application

Acrylic acid N-hydroxysuccinimide ester (NAS) is a general acrylating agent that is used in the synthesis of:
  • Acrylated hyaluronic acid (HA) hydrogel for bone regeneration applications.
  • Injectable, biodegradable, and thermosensitive copolymers for tissue engineering.
  • Imidazole-based biocompatible, aqueous quantum dots (QDs).

Packaging

1 g in glass bottle

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

hazcat

Acute Tox. 4 Oral - Eye Irrit. 2

storage_class_code

11 - Combustible Solids

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Raja Zaidatul Akhmar Raja Jamaluddin et al.
Sensors (Basel, Switzerland), 18(5) (2018-04-28)
A new biosensor for the analysis of nitrite in food was developed based on hemoglobin (Hb) covalently immobilized on the succinimide functionalized poly(n-butyl acrylate)-graphene [poly(nBA)-rGO] composite film deposited on a carbon-paste screen-printed electrode (SPE). The immobilized Hb on the poly(nBA)-rGO...
Farshad Oveissi et al.
Biomaterials science, 7(3), 926-937 (2018-12-07)
Novel hydrogels with tunable mechanical properties similar to human soft tissue have increasing applications in biomedicine, soft robotics, and biocompatible electronics. However, most of these materials require multiple-step fabrication, are not robust, and compromise bioactivity. Thus, aiming to address these...
Fred Y Shen et al.
Nature communications, 11(1), 4632-4632 (2020-09-17)
Mapping neuroanatomy is a foundational goal towards understanding brain function. Electron microscopy (EM) has been the gold standard for connectivity analysis because nanoscale resolution is necessary to unambiguously resolve synapses. However, molecular information that specifies cell types is often lost...
Protein-reactive, thermoresponsive copolymers with high flexibility and biodegradability.
Guan J, et al.
Biomacromolecules, 9(4), 1283-1292 (2008)
Avin Ramaiya et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(41), 10894-10899 (2017-10-05)
Cytoskeletal motors drive many essential cellular processes. For example, kinesin-1 transports cargo in a step-wise manner along microtubules. To resolve rotations during stepping, we used optical tweezers combined with an optical microprotractor and torsion balance using highly birefringent microspheres to...

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