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MilliporeSigma

ALD00142

Sigma-Aldrich

Ethanesulfonyl fluoride

95%

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About This Item

Empirical Formula (Hill Notation):
C2H5FO2S
CAS Number:
Molecular Weight:
112.12
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.22

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Quality Level

assay

95%

form

liquid

reaction suitability

reaction type: click chemistry

refractive index

n20/D 1.373

density

1.264 g/mL at 25 °C

SMILES string

FS(CC)(=O)=O

InChI

1S/C2H5FO2S/c1-2-6(3,4)5/h2H2,1H3

InChI key

OIBMEBLCOQCFIT-UHFFFAOYSA-N

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This Item
ALD00044ALD00178ALD00056
assay

95%

assay

95%

assay

95%

assay

95%

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

reaction suitability

reaction type: click chemistry

reaction suitability

reaction type: click chemistry

reaction suitability

reaction type: click chemistry

reaction suitability

reaction type: click chemistry

density

1.264 g/mL at 25 °C

density

-

density

1.421 at 25 °C

density

-

form

liquid

form

solid

form

liquid

form

solid

refractive index

n20/D 1.373

refractive index

-

refractive index

n/D 1.476

refractive index

-

Application

Sulfonyl fluoride motif can be used as a connector for the assembly of -SO2- linked small molecules with proteins or nucleic acids. This new click chemistry approach through sulfates is a complimentary approach to using amides and phosphate groups as linkers.

pictograms

FlameCorrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

135.0 °F

flash_point_c

57.22 °C


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Articles

In collaboration with K. Barry Sharpless and coworkers, we offer a variety of sulfonyl fluoride reagents that undergo a “Click II” reaction.

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The Sharpless Lab pursues useful new reactivity and general methods for selectively controlling chemical reactions.

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