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C121509

Sigma-Aldrich

Cystamine dihydrochloride

96%

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Synonym(s):
2,2′-Diaminodiethyl disulfide dihydrochloride, 2,2′-Dithiobis(ethylamine) dihydrochloride, Decarboxycystine dihydrochloride
Linear Formula:
NH2CH2CH2SSCH2CH2NH2 · 2HCl
CAS Number:
Molecular Weight:
225.20
Beilstein/REAXYS Number:
3616850
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

96%

form

powder

mp

217-220 °C (dec.) (lit.)

SMILES string

Cl[H].Cl[H].NCCSSCCN

InChI

1S/C4H12N2S2.2ClH/c5-1-3-7-8-4-2-6;;/h1-6H2;2*1H

InChI key

YUFRRMZSSPQMOS-UHFFFAOYSA-N

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Application

Cystamine dihydrochloride can be utilized as a building block in the synthesis of disulfide cross-linked oligodeoxyribonucleotides and psammaplin A . It can be also used to functionalize PGMA (poly(glycidyl methacrylate) microsphere) by introducing sulfhydryl groups for the further fabrication of silver nanoparticles (AgNPs).
Heparin antagonist and sulfhydryl modifying reagent

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Description
Pricing

pictograms

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signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Synthesis and characterization of disulfide cross-linked oligonucleotides
Ferentz A E, et al.
Journal of the American Chemical Society, 115(20), 9006-9014 (1993)
In situ synthesis of monodisperse silver nanoparticles on sulfhydryl-functionalized poly (glycidyl methacrylate) microspheres for catalytic reduction of 4-nitrophenol
Zhang W, et al.
Industrial & Engineering Chemistry Research, 54(25), 6480-6488 (2015)
Qianjiao Yang et al.
Molecules (Basel, Switzerland), 15(12), 8784-8795 (2010-12-04)
Psammaplin F, an unsymmetrical disulfide bromotyrosine, was isolated from the sponge Pseudoceratina purpurea in 2003. We reported here the first total synthesis of psammaplin F in 12% overall yield by employing Cleland's reagent reduction as key step. The longest linear
Nan-Fu Chiu et al.
Nanoscale research letters, 13(1), 152-152 (2018-05-17)
In this study, we propose a modified gold nanoparticle-graphene oxide sheet (AuNP-GO) nanocomposite to detect two different interactions between proteins and hybrid nanocomposites for use in biomedical applications. GO sheets have high bioaffinity, which facilitates the attachment of biomolecules to
Thorsten Overath et al.
Molecular & cellular proteomics : MCP, 11(8), 467-477 (2012-05-05)
The post-translational modification of proteins with O-GlcNAc is involved in various cellular processes including signal transduction, transcription, translation, and nuclear transport. This transient protein modification enables cells or tissues to adapt to nutrient conditions or stress. O-Glycosylation of the 26

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