MilliporeSigma
All Photos(4)

Documents

C3878

Sigma-Aldrich

Chlorogenic acid

≥95% (titration)

Sign Into View Organizational & Contract Pricing

Synonym(s):
CGA, 1,4,5-Trihydroxycyclohexanecarboxylic acid 3-(3,4-dihydroxycinnamate), 3-(3,4-Dihydroxycinnamoyl)quinic acid
Empirical Formula (Hill Notation):
C16H18O9
CAS Number:
Molecular Weight:
354.31
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥95% (titration)

form

powder

mp

210 °C (dec.) (lit.)

SMILES string

O[C@@H]1C[C@](O)(C[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@@H]1O)C(O)=O

InChI

1S/C16H18O9/c17-9-3-1-8(5-10(9)18)2-4-13(20)25-12-7-16(24,15(22)23)6-11(19)14(12)21/h1-5,11-12,14,17-19,21,24H,6-7H2,(H,22,23)/b4-2+/t11-,12-,14-,16+/m1/s1

InChI key

CWVRJTMFETXNAD-JUHZACGLSA-N

Gene Information

rat ... G6pc(25634)

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
PHR2202Y0000569PHL89175
Chlorogenic acid ≥95% (titration)

Sigma-Aldrich

C3878

Chlorogenic acid

Chlorogenic Acid Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR2202

Chlorogenic Acid

Chlorogenic acid European Pharmacopoeia (EP) Reference Standard

Y0000569

Chlorogenic acid

Chlorogenic acid phyproof® Reference Substance

PHL89175

Chlorogenic acid

form

powder

form

-

form

-

form

solid

mp

210 °C (dec.) (lit.)

mp

210 °C (dec.) (lit.)

mp

210 °C (dec.) (lit.)

mp

210 °C (dec.) (lit.)

Gene Information

rat ... G6pc(25634)

Gene Information

-

Gene Information

-

Gene Information

-

General description

Chlorogenic acid is a bioactive polyphenolic compound mainly found in many plants, such as coffee. It is a potent neuroprotectant and also possesses antiviral, antifungal, antioxidant and antitumor properties. CGA may also be involved in regulating glucose and lipid metabolism and improving insulin sensitivity.
Chlorogenic acid is a cinnamate ester used as a reducing agent and stabilizer in bimetallic nanoparticle synthesis.

Caution

May yield a hazy solution in ethanol

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 5

1 of 5

D-(−)-Quinic acid 98%

Sigma-Aldrich

138622

D-(−)-Quinic acid

Rutin hydrate ≥94% (HPLC), powder

Sigma-Aldrich

R5143

Rutin hydrate

p-Coumaric acid ≥98.0% (HPLC)

Sigma-Aldrich

C9008

p-Coumaric acid

Neochlorogenic acid phyproof® Reference Substance

PHL80504

Neochlorogenic acid

Controlled green synthesis of Au-Pt bimetallic nanoparticles using chlorogenic acid
Chen R, et al.
Research on Chemical Intermediates, 47, 4051-4066 (2021)
Chlorogenic acid and caffeic acid are absorbed in humans
Olthof MR
The Journal of Nutrition, 131(1), 66-71 (2001)
Shp2 regulates chlorogenic acid-induced proliferation and adipogenic differentiation of bone marrow-derived mesenchymal stem cells in adipogenesis
Zhou RP
Molecular Medicine Reports, 11(6), 4489-4495 (2015)
Computational screen and experimental validation of anti-influenza effects of quercetin and chlorogenic acid from traditional Chinese medicine
Liu Z
Scientific Reports, 6, 19095-19095 (2016)
Chlorogenic acid and coffee prevent hypoxia-induced retinal degeneration
Jang H
Journal of Agricultural and Food Chemistry, 62(1), 182-191 (2013)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service