C94408

4-Cyano-4-phenylpiperidine hydrochloride

96%

• Synonym(s): 4-Phenyl-4-piperidinecarbonitrile hydrochloride
• Empirical Formula (Hill Notation): C₁₂H₁₄N₂ · HCl
• CAS Number: 51304-58-6
• Molecular Weight: 222.71
• EC Number: 257-124-5
• MDL number: MFCD00012775
• UNSPSC Code: 12352100
• PubChem Substance ID: 24892998
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: 96%
• form: solid
• mp: 208-210 °C (lit.)
• SMILES string: Cl.N#CC1(CCNCC1)c2ccccc2
• InChI: 1S/C12H14N2.ClH/c13-10-12(6-8-14-9-7-12)11-4-2-1-3-5-11;/h1-5,14H,6-9H2;1H
• InChI key: CQPHZBOPSZGTJM-UHFFFAOYSA-N

Description

Application

Reactant for synthesis of:

• CCR5 antagonists derived at the N-terminal of the piperidine ring
• Substituted piperidines as lignads of chemokine receptor 5 and inhibitors of HIV-1
• Functionalized nitrogen heterocycles by radical decarboxylation of β- and γ- amino acids
• Benzovesamicol analogs as potential imaging probes for vesicular acetylcholine transporters
• Neurotransmitter transporter inhibitors with activity at dopamine receptor sites
• α1a Adrenoceptor-selective antagonists

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H312 + H332,H315,H319,H335
• pcodes: P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves