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D13208

Sigma-Aldrich

1,4-Diaminobutane

99%

Synonym(s):

1,4-Butanediamine, Putrescine, Tetramethylenediamine

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About This Item

Linear Formula:
NH2(CH2)4NH2
CAS Number:
Molecular Weight:
88.15
Beilstein/REAXYS Number:
605282
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

99%

form

solid

expl. lim.

9.08 %

refractive index

n20/D 1.457 (lit.)

bp

158-160 °C (lit.)

mp

25-28 °C (lit.)

density

0.877 g/mL at 25 °C (lit.)

SMILES string

NCCCCN

InChI

1S/C4H12N2/c5-3-1-2-4-6/h1-6H2

InChI key

KIDHWZJUCRJVML-UHFFFAOYSA-N

Gene Information

rat ... Odc1(24609)

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Related Categories

Application

GABA precursor in many biological systems and synthon for amido-ureas.

pictograms

Skull and crossbonesCorrosion

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

wgk_germany

WGK 1

flash_point_f

113.0 °F

flash_point_c

45 °C

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


Certificates of Analysis (COA)

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Journal of the Chemical Society. Perkin Transactions 1, 3179-3179 (1992)
M C de Mello et al.
Neurochemistry international, 22(3), 249-253 (1993-03-01)
Cultured retina cells from chick embryos took up [3H]putrescine and approx 10.8% of the incorporated amine was converted into [3H]GABA. The putrescine-derived GABA accumulated in a pool that was released in the medium at a rate corresponding to 3.66% of
Juhani Jänne et al.
European journal of biochemistry, 271(5), 877-894 (2004-03-11)
The polyamines putrescine, spermidine and spermine are organic cations shown to participate in a bewildering number of cellular reactions, yet their exact functions in intermediary metabolism and specific interactions with cellular components remain largely elusive. Pharmacological interventions have demonstrated convincingly
Chi Yang et al.
PloS one, 7(10), e47314-e47314 (2012-10-17)
The phosphate starvation response in bacteria has been studied extensively for the past few decades and the phosphate-limiting signal is known to be mediated via the PhoBR two-component system. However, the global DNA binding profile of the response regulator PhoB
A Raina et al.
Medical biology, 53(3), 121-147 (1975-06-01)
The biochemistry and biological function of the naturally occurring polyamines, putrescine, spermidine, and spermine, have been reviewed with special reference to animal organisms. These compounds are universally distributed in all living material. Their biosynthesis from ornithine and methionine is accurately

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