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D49504

Sigma-Aldrich

Dibutyl sebacate

technical grade

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Synonym(s):
Decanedioic acid dibutyl ester, Sebacic acid dibutyl ester
Linear Formula:
[-(CH2)4CO2(CH2)3CH3]2
CAS Number:
Molecular Weight:
314.46
Beilstein/REAXYS Number:
1798308
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

grade

technical grade

form

liquid

refractive index

n20/D 1.441 (lit.)

bp

178-179 °C/3 mmHg (lit.)

solubility

hexane, toluene, ethanol and acetone: soluble
water and propylene glycol: insoluble

density

0.936 g/mL at 25 °C (lit.)

SMILES string

CCCCOC(=O)CCCCCCCCC(=O)OCCCC

InChI

1S/C18H34O4/c1-3-5-15-21-17(19)13-11-9-7-8-10-12-14-18(20)22-16-6-4-2/h3-16H2,1-2H3

InChI key

PYGXAGIECVVIOZ-UHFFFAOYSA-N

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General description

Dibutyl sebacate(DBS) is a lipophilic dibutyl ester that can be used as a plasticizer with low solubility in water.

Application

DBS can be used as a plasticizer for the formation of ethylcellulose based coating membranes which can be potentially used in drug delivery systems. It may also be used as a plasticizer during the fabrication of electronic artificial tongue sensors for analyzing the intensity of olive oils.

wgk_germany

WGK 1

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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GC method for determining polyadipate plasticizers in foods: transesterification to dibutyl adipate, conversion to migrating polyadipate.
Biedermann M and Grob K
Chromatographia, 64(9-10), 543-552 (2006)
Sensory intensity assessment of olive oils using an electronic tongue.
Veloso ACA, et al.
Talanta, 146(3), 585-593 (2016)
Physico-mechanical analysis of free ethylcellulose films plasticized with incremental weight percents of dibutyl sebacate.
Kangarlou S and Haririan I
Iranian Journal of Pharmaceutical Sciences, 3(3), 135-142 (2007)
T Quinten et al.
Drug development and industrial pharmacy, 37(2), 149-159 (2010-07-10)
It was the aim of the present study to develop sustained-release matrix tablets by means of injection molding of ethylcellulose (EC) and polyethylene oxide (PEO) mixtures and to evaluate the influence of process temperature, matrix composition, and viscosity grade of
Thomas Quinten et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 71(1), 145-154 (2008-05-31)
The aim of this study was to develop sustained-release matrix tablets by means of injection moulding and to evaluate the influence of process temperature, matrix composition (EC and HPMC concentration) and viscosity grade of ethylcellulose (EC) and hydroxypropylmethylcellulose (HPMC) on

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