D55008

Dichloroacetyl chloride

Name: Dichloroacetyl chloride
Brand: ALDRICH
Price: 78 USD
Availability: InStock

98%

Synonym(s):

α,α-Dichloroacetyl chloride, 2,2-Dichloroacetyl chloride, Dichloracetyl chloride, Dichloroacetic acid chloride, Dichloroethanoyl chloride

Slide 1 of 2

Sign Into View Organizational & Contract Pricing

Select a Size

100 G

$78.00

500 G

$255.00

$78.00

Available to ship TODAYDetails

Request a Bulk Order

About This Item

Linear Formula:

Cl₂CHCOCl

CAS Number:

79-36-7

Molecular Weight:

147.39

Beilstein/REAXYS Number:

1209426

EC Number:

201-199-9

MDL number:

MFCD00000840

UNSPSC Code:

12352100

PubChem Substance ID:

24893840

NACRES:

NA.22

Key Documents

View All Documentation

Quality Level

200

assay

98%

form

liquid

refractive index

n20/D 1.46 (lit.)

bp

107-108 °C (lit.)

density

1.532 g/mL at 25 °C (lit.)

SMILES string

ClC(Cl)C(Cl)=O

InChI

1S/C2HCl3O/c3-1(4)2(5)6/h1H

InChI key

FBCCMZVIWNDFMO-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Chemical Building Blocks

Organic Building Blocks

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item	151599	109614	11019
Sigma-Aldrich D55008 Dichloroacetyl chloride	Sigma-Aldrich 151599 Trichloroacetyl chloride	Sigma-Aldrich 109614 Butyryl chloride	Sigma-Aldrich 11019 Aluminum chloride
assay 98%	assay 99%	assay 98%	assay ≥98%
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
refractive index n20/D 1.46 (lit.)	refractive index n20/D 1.470 (lit.)	refractive index n20/D 1.412 (lit.)	refractive index -
form liquid	form liquid	form -	form powder
density 1.532 g/mL at 25 °C (lit.)	density 1.629 g/mL at 25 °C (lit.)	density 1.026 g/mL at 25 °C (lit.)	density -
bp 107-108 °C (lit.)	bp 114-116 °C (lit.)	bp 102 °C (lit.)	bp -

pictograms

GHS08,GHS05,GHS09

signalword

Danger

hcodes

H314,H350,H400

pcodes

P202 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Aquatic Acute 1 - Carc. 1B - Eye Dam. 1 - Skin Corr. 1A

supp_hazards

EUH071

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 2

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Inhalation carcinogenesis of various alkylating agents.

A R Sellakumar et al.

Journal of the National Cancer Institute, 79(2), 285-289 (1987-08-01)

A series of earlier studies showed that inhalation exposures of rats to three water-reactive electrophilic compounds produced brisk yields of nasal cancer even when the animals were exposed for only 30 days (6 hr/day X 5 day/wk). In addition, carcinogenic

Time-dependent autoimmune response of dichloroacetyl chloride in female MRL +/+ mice.

M F Khan et al.

Immunopharmacology and immunotoxicology, 19(2), 265-277 (1997-05-01)

Welders are exposed to dichloroacetyl chloride (DCAC) when trichloroethene (TCE) is used as a degreasing agent. Human exposure to TCE and tetrachloroethane can also lead to formation of DCAC in situ through metabolism. Due to its strong acylating property, it

Transcriptomic analysis reveals early signs of liver toxicity in female MRL +/+ mice exposed to the acylating chemicals dichloroacetyl chloride and dichloroacetic anhydride.

Rolf König et al.

Chemical research in toxicology, 21(3), 572-582 (2008-02-26)

Dichloroacetyl chloride (DCAC) is a reactive metabolite of trichloroethene (TCE). TCE and its metabolites have been implicated in the induction of organ-specific and systemic autoimmunity, in the acceleration of autoimmune responses, and in the development of liver toxicity and hepatocellular

Autoimmune response in MRL+/+ mice following treatment with dichloroacetyl chloride or dichloroacetic anhydride.

Ping Cai et al.

Toxicology and applied pharmacology, 216(2), 248-255 (2006-06-30)

Dichloroacetyl chloride (DCAC) is formed from trichloroethene (TCE), which is implicated in inducing/accelerating autoimmune response. Due to its potent acylating activity, DCAC may convert proteins to neo-antigens and thus could induce autoimmune responses. Dichloroacetic anhydride (DCAA), which is a similar

Anti-malondialdehyde antibodies in MRL+/+ mice treated with trichloroethene and dichloroacetyl chloride: possible role of lipid peroxidation in autoimmunity.

M F Khan et al.

Toxicology and applied pharmacology, 170(2), 88-92 (2001-02-13)

Trichloroethene (TCE) and one of its metabolites dichloroacetyl chloride (DCAC) are known to induce/accelerate autoimmune (AI) response in MRL+/+ mice as evident from anti-nuclear, anti-ssDNA, anti-cardiolipin, and DCAC-specific antibodies in the serum (Khan et al., Toxicol. Appl. Pharmacol. 134, 155-160

View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Dichloroacetyl chloride